YRC Public Data Repository - Protein Structure Prediction

Protein:	psp3
Organism:	Schizosaccharomyces pombe
Length:	451 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for psp3.

Description	E-value	Query Range	Subject Range
gi\|1749666, gi\|1... - gi\|1749666\|dbj\|BAA13890.1\| unnamed protein product [Schizosaccharomyces pombe], gi\|11265086\|pir\|\|T43...	388.0	[0..1]	[451..5]
gi\|116193325, gi... - gi\|88182293\|gb\|EAQ89761.1\| hypothetical protein CHGG_06380 [Chaetomium globosum CBS 148.51], gi\|1161...	311.0	[0..42]	[449..5]
gi\|17402485 - gi\|17402485\|emb\|CAD13274.1\| protease PR1H [Metarhizium anisopliae var. anisopliae] gi\|17402485 - gi\|17402485\|emb\|CAD13274.1\| protease PR1H [Metarhizium anisopliae var. anisopliae]	309.0	[0..37]	[449..3]
gi\|171680111 - gi\|171680111\|ref\|XP_001905001.1\| unnamed protein product [Podospora anserina] gi\|7400480, gi\|1... - gi\|7400480\|gb\|AAC03564.2\| subtilisin-like serine protease [Podospora anserina], gi\|170939682\|emb\|CAP...	308.0	[0..62]	[449..26]
gi\|40746955, gi\|... - gi\|67515913\|ref\|XP_657842.1\| hypothetical protein AN0238.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	307.0	[0..35]	[449..83]
gi\|16215673 - gi\|16215673\|emb\|CAC95047.1\| subtilisin-like serine protease PR1H [Metarhizium anisopliae var. acridu...	306.0	[0..37]	[449..3]
gi\|15808807 - gi\|15808807\|gb\|AAL08510.1\|AF413106_1 subtilase [Ophiostoma piliferum]	306.0	[0..45]	[449..2]
gi\|111182171, gi... - gi\|118498761\|gb\|ABK96987.1\| serine protease p2 [Chaetomium thermophilum], gi\|111182171\|gb\|ABH07518.1...	305.0	[0..64]	[449..28]
ALP2_ASPFC - Alkaline protease 2 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=alp2 PE=3 SV... gi\|2143220, gi\|5... - gi\|5139328\|emb\|CAB45520.1\| serine proteinase [Aspergillus fumigatus], gi\|2143220\|emb\|CAA73782.1\| cel... ALP2_ASPFU - Alkaline protease 2 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)...	304.0	[0..42]	[449..5]

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Predicted Domain #1

Region A:
Residues: [1-366]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVSWISGLL LVAHLAPSSA FNPLRFFLDD TFSSGATEEH FMGPSDDGFA LQQPTNYDPS  60
   61 MPFPLDESAS AAVDAVSNNY IVMFKPSVDK SKLEQHHRWI EHLHEKRSLD FKDVSTFLMK 120
  121 HTFEIGDAFL GYAGRFSPWL VAELQKHPDI ALVEPDRVMH VMTEQTFAPW GLARVSHRKK 180
  181 LGFFTMTRYQ YNETAGEGVT AYVIDTGINI EHQDFQGRAT WGATIPTGEG EVDDHGHGTH 240
  241 VAGTIAGKTF GVSKNAKLVA VKVMRADGTG TVSDIIKGIE FAFKQSKKDK ESIASVVNMS 300
  301 IGGDASTALD LAVNAAIAGG LFFAVAAGND AEDACGTSPA RVSNAMTVGA STWNDQIASF 360
  361 SNIGSC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.522879
Match:	1t1eA
Description:	High Resolution Crystal Structure of the Intact Pro-Kumamolisin, a Sedolisin Type Proteinase (previously called Kumamolysin or KSCP)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	4.68838733699853	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	4.20928698248021	bayes_pls_golite062009
endopeptidase activity	3.45296270246929	bayes_pls_golite062009
hydrolase activity	3.36483239319728	bayes_pls_golite062009
serine hydrolase activity	1.90036575189745	bayes_pls_golite062009
serine-type peptidase activity	1.89198766955068	bayes_pls_golite062009
serine-type endopeptidase activity	1.23150012549143	bayes_pls_golite062009
binding	0.694655140210979	bayes_pls_golite062009
catalytic activity	0.597535457699629	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [367-451]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDIFAPGSLI LSDWIGSNRA SMILSGTSMA SPHVAGLAAY FISLDPSLAN HPVELKKYML  60
   61 KFALKDLLNG IPEDTPNVLA FNNYE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.522879
Match:	1ic6A
Description:	Proteinase K
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: