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View Structure Prediction Details

Protein: SPAC17D4.03c
Organism: Schizosaccharomyces pombe
Length: 732 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC17D4.03c.

Description E-value Query
Range
Subject
Range
gi|38537139 - gi|38537139|gb|AAR23528.1| metal tolerance protein 1; MTP1 [Populus balsamifera subsp. trichocarpa x...
249.0 [0..313] [723..20]
gi|59275989 - gi|59275989|dbj|BAD89562.1| NTMTP1A [Nicotiana tabacum]
243.0 [0..336] [725..41]
gi|16550925 - gi|16550925|gb|AAL25646.1|AF197329_1 zinc transporter [Eucalyptus grandis]
243.0 [0..346] [725..54]
gi|73959985 - gi|73959985|ref|XP_537050.2| PREDICTED: similar to zinc transporter like 2 [Canis familiaris]
241.0 [0..338] [727..322]
gi|59275987 - gi|59275987|dbj|BAD89561.1| NGMTP1 [Nicotiana glauca]
241.0 [0..333] [725..38]
ZnT35C-PA - This gene is referred to in FlyBase by the symbol Dmel\ZnT35C (CG3994, FBgn0028516). It is a protein...
gi|220949100 - gi|220949100|gb|ACL87093.1| ZnT35C-PA [synthetic construct]
236.0 [0..334] [723..74]
gi|40287444 - gi|40287444|gb|AAR83907.1| heavy metal transporter MTP1 [Thlaspi caerulescens]
229.0 [0..340] [723..44]

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Predicted Domain #1
Region A:
Residues: [1-213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVNSSAFER TNRFPSFPVL KDDQKTSSDS IAAAKKKDLL SLISSKSLLS SETLGWFSVI  60
   61 CAFSITGSGL EVNTMSIPFY LIFGIFAFVS FTTQYLGIYS FSFQPFQLLN VIIASLSMVF 120
  121 ITLGAFVLGT LDTTCLLLLA FKLFFIRNDP TPFNARSANL KNYIAFPICL FVINHILILL 180
  181 GYFQCSYSVF YASVFYILLG VFIRVFYLVN KEK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [214-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEKKELAFLF SSIVVACLIQ FNVLPLGTIN LSVTRFTILC FMQIFCINWD GIARIQFYLG  60
   61 KFDISLIMAL ISAIINKTAS QNSIKIISCL YQVGFCFFKI GSSITANLKL PDNSRIYRLY 120
  121 NDFIVNGVLA DKESRSIFYF FLLNVSYMFV QVIYGLWTNS LGLISDAIHM AFDCIAILVG 180
  181 LVATTLAKMP LNYAYPFGFA KIEALSGFTN GIFLVLISFS IVGEALYRLF HPPQMNTDQL 240
  241 LLVSFLGLVV NLVGIL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.61
Match: 2qfiA
Description: No description for 2qfiA was found.

Predicted functions:

Term Confidence Notes
cation transmembrane transporter activity 5.92891514013737 bayes_pls_golite062009
ion transmembrane transporter activity 5.84249545493637 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.47016841740423 bayes_pls_golite062009
transporter activity 3.98293753989079 bayes_pls_golite062009
transmembrane transporter activity 3.88313530012213 bayes_pls_golite062009
substrate-specific transporter activity 3.61385992680996 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.37050743362323 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 2.19121021485065 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.90853228829647 bayes_pls_golite062009
cation channel activity 1.44274272281585 bayes_pls_golite062009
efflux transmembrane transporter activity 1.28777469980862 bayes_pls_golite062009
binding 1.28505954375411 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 1.20401058605752 bayes_pls_golite062009
ion channel activity 0.914570427745709 bayes_pls_golite062009
passive transmembrane transporter activity 0.878658430633935 bayes_pls_golite062009
channel activity 0.878658430633935 bayes_pls_golite062009
substrate-specific channel activity 0.85991028753625 bayes_pls_golite062009
active transmembrane transporter activity 0.475232131680683 bayes_pls_golite062009
protein binding 0.318355149027855 bayes_pls_golite062009
cadmium ion transmembrane transporter activity 0.250934822515216 bayes_pls_golite062009
iron ion transmembrane transporter activity 0.186398867523746 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [470-732]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFNHGHNHDH GSHHHHSHSN HSMCLPNTTN DINIFEEFEE EKDNVEAQKM GYTNDDHVSQ  60
   61 HEHTHENSQE HHHEHNHNHD HIHKYNEKCD HESISLQNLD NDHHCHHHHE NHNMHGIFLH 120
  121 IIADTMGSVG VIVSTILIQW FSWTGFDPLA SLIIAALIFV SVLPLIKDSA KNLLSVTDPE 180
  181 SEYLLKQCLS NISLSNSVIS LSNPKFWTNE RGEVYGILHI QVSIDGDLNV VRNEVFRKLS 240
  241 IAVPNLKHIC IQSERPNNCW CGK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.30103
Match: 2qfiA
Description: No description for 2qfiA was found.

Predicted functions:

Term Confidence Notes
cation transmembrane transporter activity 6.3253503604398 bayes_pls_golite062009
ion transmembrane transporter activity 6.22189384650962 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.82185991246167 bayes_pls_golite062009
transporter activity 4.27173462293249 bayes_pls_golite062009
transmembrane transporter activity 4.18558383943492 bayes_pls_golite062009
substrate-specific transporter activity 3.94511592355578 bayes_pls_golite062009
metal ion transmembrane transporter activity 2.43294134632841 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 2.32644140472297 bayes_pls_golite062009
efflux transmembrane transporter activity 1.98656970252979 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.95281540802467 bayes_pls_golite062009
cation channel activity 1.55011961058299 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 1.31663166812163 bayes_pls_golite062009
binding 1.27456652114636 bayes_pls_golite062009
ion channel activity 1.01093555209783 bayes_pls_golite062009
passive transmembrane transporter activity 0.963824080292546 bayes_pls_golite062009
channel activity 0.963824080292546 bayes_pls_golite062009
substrate-specific channel activity 0.948079854416241 bayes_pls_golite062009
cadmium ion transmembrane transporter activity 0.661906409169955 bayes_pls_golite062009
active transmembrane transporter activity 0.490905558612378 bayes_pls_golite062009
iron ion transmembrane transporter activity 0.376948884172728 bayes_pls_golite062009
protein binding 0.311357063667067 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle