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View Structure Prediction Details

Protein: gde1
Organism: Schizosaccharomyces pombe
Length: 1076 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gde1.

Description E-value Query
Range
Subject
Range
gi|115620299 - gi|115620299|ref|XP_001199201.1| PREDICTED: similar to ankyrin 2,3/unc44 [Strongylocentrotus purpura...
601.0 [0..2] [909..206]
gi|157106389, gi... - gi|157106389|ref|XP_001649301.1| ankyrin 2,3/unc44 [Aedes aegypti], gi|108868849|gb|EAT33074.1| anky...
583.0 [0..24] [930..1]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLENDLQKVV NLFNTRIVQL DNYVTRLSTE KSPNTEITQA LSSSYEAEEK AKQLKELDFR  60
   61 LQQLSSFCEW NKLAFEKLAA NMDKHLGTER LVTFYEQKVC KLDFANSSKI YESMIALKAL 120
  121 NSSQNDSEVK DKLEKL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [137-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIHHPLKKDL LAFIQLDIAA EVVTACINAP DSVLVDILAA SIIAGAKACM REVIGRIGLR  60
   61 SECLASALRR AINNLCGPDE GVLYFLEVLK QICSVVYVDS YHSNRLLSRI LLVERNSKG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.0
Match: 2f8xK
Description: No description for 2f8xK was found.

Predicted Domain #3
Region A:
Residues: [256-658]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSVMHSVAKL GWAGLCSKFC EIVSSIPDSE PLNWMLPCWR DVMHDTPLTL AIKGNHVEAL  60
   61 HALLSAQDKE TTSTKPGPVP PLVLTCCVGD YDLIVEELIL AGFNPNEVDA SSNTALHTAV 120
  121 RYNRPECVKM LLKLGANPSA RDFLNSWTPL MLASATGLSE IVSILVASGA SVDEVDSSGW 180
  181 TAMEQAVVRG YLHLADKLRT QVALSDKPVN LHTLYIKASS SEMRSRKRAM DLQLSRSVVI 240
  241 IRISDLAGRI RVSLQGDDAV YVSGRSPSFA ASRPSSVDFM SQSTDSLSKN DTTASNGSMT 300
  301 PSSSQNNSVI IDIPRSHFDN AGEVCLENLA EPDEIADDSI HLHYDAAQEN SPQPVNGSSP 360
  361 PYELVFVTRN TEEATITIDL LANRSHKILG RTVCCLTSLV SDL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.69897
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.819335581329918 bayes_pls_golite062009
protein binding 0.710332507917693 bayes_pls_golite062009
calcium-independent phospholipase A2 activity 0.621306773219824 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [659-727]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNHMQSLKPL APLPLLSSKT LKPIAHVNAD VLISKVTVDD RFSSNDGIST PALSLEAVSN  60
   61 VSRTALEDA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [728-1076]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERSLHKSATT TSESGKSNGV AVIGHRGLGK NQPDRLSLQL GENTLQSFIK AADLGASYVE  60
   61 LDVQMTKDMV PVVYHDFIVN ETGTDAQVHS LTLEQFLGAS HSPSEEIKDD ASDIQQKRRP 120
  121 RAYSSSFTPS GSQVNFGEFA EENARLKPKV YKGNALGHTI CAPFTTLKDV LKEVPQSVGL 180
  181 NVEFKYPMLS EAEEEKLLPI AYDYNFYVDT ILSIIKKYGG KRKYIFSSFN PDICILLSLK 240
  241 STNPVLFLTE GGTAYRTDVR AASLRQALKF ASQWSFLGIV SACEPLIMCP RLIKAVKQLG 300
  301 LSCYTYGVLN NDVDNVRRQV RFGVDAVIVD NVLAIRRALN QYDESLESD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.39794
Match: 1t8qA
Description: Structural genomics, Crystal structure of Glycerophosphoryl diester phosphodiesterase from E. coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycerophosphodiester phosphodiesterase activity 4.27697417361287 bayes_pls_golite062009
phosphoric diester hydrolase activity 3.6633363681844 bayes_pls_golite062009
phospholipase activity 3.3535603060637 bayes_pls_golite062009
phosphoric ester hydrolase activity 3.27299307330343 bayes_pls_golite062009
phospholipase C activity 2.81479108775786 bayes_pls_golite062009
inositol or phosphatidylinositol phosphodiesterase activity 2.13368269358874 bayes_pls_golite062009
phosphoinositide phospholipase C activity 2.13368269358874 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.48964499825589 bayes_pls_golite062009
hydrolase activity 1.41001330359992 bayes_pls_golite062009
lipase activity 1.30779031242608 bayes_pls_golite062009
phosphatidylglycerol phospholipase C activity 1.28645679518658 bayes_pls_golite062009
catalytic activity 1.22328099675039 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle