YRC Public Data Repository - Protein Structure Prediction

Protein:	dpb3
Organism:	Schizosaccharomyces pombe
Length:	199 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dpb3.

Description	E-value	Query Range	Subject Range
gi\|109078679 - gi\|109078679\|ref\|XP_001110513.1\| PREDICTED: H2A histone family, member Y isoform 2 [Macaca mulatta] gi\|114601783, gi... - gi\|114601785\|ref\|XP_001168429.1\| PREDICTED: similar to histone macroH2A1.1 isoform 3 [Pan troglodyte... gi\|4758496, gi\|3... - gi\|93141020\|ref\|NP_001035248.1\| H2A histone family, member Y isoform 2 [Homo sapiens], gi\|4758496\|re...	173.0	[0..4]	[199..3]
gi\|114601791 - gi\|114601791\|ref\|XP_001168478.1\| PREDICTED: similar to histone macroH2A1.1 isoform 5 [Pan troglodyte...	173.0	[0..4]	[199..3]
gi\|87578157, gi\|... - gi\|87578157\|gb\|AAI13288.1\| H2A histone family, member Y [Bos taurus], gi\|114052404\|ref\|NP_001039805....	172.0	[0..4]	[199..3]
H2AY_RAT - Core histone macro-H2A.1 OS=Rattus norvegicus GN=H2afy PE=1 SV=4	171.0	[0..4]	[199..3]
gi\|542149408\|ref... - PREDICTED: core histone macro-H2A.1-like isoform X1 [Zonotrichia albicollis] gi\|224068058 - gi\|224068058\|ref\|XP_002187530.1\| PREDICTED: H2A histone family, member Y [Taeniopygia guttata] H2AY_CHICK - Core histone macro-H2A.1 OS=Gallus gallus GN=H2AFY PE=1 SV=3	170.0	[0..4]	[199..3]
gi\|73971330 - gi\|73971330\|ref\|XP_538635.2\| PREDICTED: similar to H2A histone family, member Y isoform 3 [Canis fam...	170.0	[0..4]	[199..43]

Back

Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDPTNNNDS ETKPNPATYW KSRFPVARIK KIMQADQDVG KVAQVTPVIM SKALELFMQS  60
   61 IIQESCKQTR LHQAKRVTVS HLKHAVQSVE QFDFLQDIVE KVPDAPPIKA ERKTKRPRAR 120
  121 RAANEGEHN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.69897
Match:	1aoiC
Description:	Histone H2A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA-directed DNA polymerase activity	7.30463919195401	bayes_pls_golite062009
DNA polymerase activity	7.25909396656216	bayes_pls_golite062009
nucleotidyltransferase activity	4.91761894051618	bayes_pls_golite062009
DNA binding	3.33590750206299	bayes_pls_golite062009
nucleic acid binding	3.33150991098513	bayes_pls_golite062009
transcription regulator activity	2.74104602193943	bayes_pls_golite062009
binding	2.68226682911828	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	2.18081531032351	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.71814239259767	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.71244156762178	bayes_pls_golite062009
transferase activity	1.4922191078713	bayes_pls_golite062009
protein binding	1.47714270074552	bayes_pls_golite062009
transcription factor activity	1.43258372806556	bayes_pls_golite062009
transcription activator activity	0.56890094816403	bayes_pls_golite062009
transcription factor binding	0.48055497002898	bayes_pls_golite062009
transcription cofactor activity	0.36684586697198	bayes_pls_golite062009
transcription repressor activity	0.0502944474168801	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [130-199]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESVPAKKVKK NTVKEEEIEK DDESATTETP VKEEPTGEET EADHEEKASV DHGNFSDKTT  60
   61 SEASSASGDE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	7.39794
Match:	1zr5A
Description:	Crystal structure of the macro-domain of human core histone variant macroH2A1.2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: