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View Structure Prediction Details

Protein: rrp8
Organism: Schizosaccharomyces pombe
Length: 318 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rrp8.

Description E-value Query
Range
Subject
Range
gi|114636509 - gi|114636509|ref|XP_508260.2| PREDICTED: similar to KIAA0409 [Pan troglodytes]
184.0 [0..9] [318..205]
RRP8_RAT - Ribosomal RNA-processing protein 8 OS=Rattus norvegicus GN=Rrp8 PE=1 SV=1
184.0 [0..8] [318..166]
gi|74178549 - gi|74178549|dbj|BAE32523.1| unnamed protein product [Mus musculus]
183.0 [0..9] [318..213]
gi|2662099 - gi|2662099|dbj|BAA23705.1| KIAA0409 [Homo sapiens]
183.0 [0..9] [318..174]
RRP8_ARATH - Ribosomal RNA-processing protein 8 OS=Arabidopsis thaliana GN=At5g40530 PE=2 SV=1
175.0 [0..18] [318..2]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKVDWDLGP VSKSASDQTK ESRKEKKRKK GERKNVGDKG EKLNEKVLKK AKSVTTNNSL  60
   61 KSEIKKEKSV PSIKEKNKGD AKHTKLTSLQ QKMKDKLDGA NFRWINEQLY T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [112-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TESDKAVQMF KENPDLFDIY HAGFRYQVEG WPENPVDIFI QHLKIRFEHS NAKKKNNIVI  60
   61 ADLGCGEAKI ASTFRKSRSL QVHSFDLVAP NEHVVACDIA NVPMADETVD IAVFCLSLMG 120
  121 TNWQSFLKEA YRILKVGGLL WVAEIKSRFS DKSGEVFAKE LPKLGFETKS IQLQNKMFTL 180
  181 FEFKKVPVHG KCEELPPILS ACIYKRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.045757
Match: 1tpyA
Description: Structure of the cyclopropane synthase MmaA2 from Mycobacterium tuberculosis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
S-adenosylmethionine-dependent methyltransferase activity 3.15840198589582 bayes_pls_golite062009
methyltransferase activity 3.08059259177729 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 2.99781997782052 bayes_pls_golite062009
rRNA methyltransferase activity 2.89157295612945 bayes_pls_golite062009
RNA methyltransferase activity 2.57273894921779 bayes_pls_golite062009
N-methyltransferase activity 2.26670816231281 bayes_pls_golite062009
tRNA methyltransferase activity 1.55242772787972 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 1.21404153202137 bayes_pls_golite062009
transferase activity 1.07321114919891 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 1.03293084629981 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.954020631547781 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.742142092552002 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
RNA binding 0.417524996559564 bayes_pls_golite062009
binding 0.383237930789959 bayes_pls_golite062009
rRNA (uridine-2'-O-)-methyltransferase activity 0.15443733645953 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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