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View Structure Prediction Details

Protein: rrp8
Organism: Schizosaccharomyces pombe
Length: 318 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rrp8.

Description E-value Query
Range
Subject
Range
gi|114636509 - gi|114636509|ref|XP_508260.2| PREDICTED: similar to KIAA0409 [Pan troglodytes]
184.0 [0..9] [318..205]
RRP8_RAT - Ribosomal RNA-processing protein 8 OS=Rattus norvegicus GN=Rrp8 PE=1 SV=1
184.0 [0..8] [318..166]
gi|74178549 - gi|74178549|dbj|BAE32523.1| unnamed protein product [Mus musculus]
183.0 [0..9] [318..213]
gi|2662099 - gi|2662099|dbj|BAA23705.1| KIAA0409 [Homo sapiens]
183.0 [0..9] [318..174]
RRP8_ARATH - Ribosomal RNA-processing protein 8 OS=Arabidopsis thaliana GN=At5g40530 PE=2 SV=1
175.0 [0..18] [318..2]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKVDWDLGP VSKSASDQTK ESRKEKKRKK GERKNVGDKG EKLNEKVLKK AKSVTTNNSL  60
   61 KSEIKKEKSV PSIKEKNKGD AKHTKLTSLQ QKMKDKLDGA NFRWINEQLY T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [112-318]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TESDKAVQMF KENPDLFDIY HAGFRYQVEG WPENPVDIFI QHLKIRFEHS NAKKKNNIVI  60
   61 ADLGCGEAKI ASTFRKSRSL QVHSFDLVAP NEHVVACDIA NVPMADETVD IAVFCLSLMG 120
  121 TNWQSFLKEA YRILKVGGLL WVAEIKSRFS DKSGEVFAKE LPKLGFETKS IQLQNKMFTL 180
  181 FEFKKVPVHG KCEELPPILS ACIYKRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.045757
Match: 1tpyA
Description: Structure of the cyclopropane synthase MmaA2 from Mycobacterium tuberculosis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
S-adenosylmethionine-dependent methyltransferase activity 3.15840198589582 bayes_pls_golite062009
methyltransferase activity 3.08059259177729 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 2.99781997782052 bayes_pls_golite062009
rRNA methyltransferase activity 2.89157295612945 bayes_pls_golite062009
RNA methyltransferase activity 2.57273894921779 bayes_pls_golite062009
N-methyltransferase activity 2.26670816231281 bayes_pls_golite062009
tRNA methyltransferase activity 1.55242772787972 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 1.21404153202137 bayes_pls_golite062009
transferase activity 1.07321114919891 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 1.03293084629981 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.954020631547781 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.742142092552002 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
RNA binding 0.417524996559564 bayes_pls_golite062009
binding 0.383237930789959 bayes_pls_golite062009
rRNA (uridine-2'-O-)-methyltransferase activity 0.15443733645953 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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