YRC Public Data Repository - Protein Structure Prediction

Protein:	tbp1
Organism:	Schizosaccharomyces pombe
Length:	231 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tbp1.

Description	E-value	Query Range	Subject Range
gi\|17298076 - gi\|17298076\|dbj\|BAB78512.1\| TATA-box binding protein [Oryzias latipes]	335.0	[0..1]	[230..85]
TBP_XENTR - TATA-box-binding protein OS=Xenopus tropicalis GN=tbp PE=2 SV=1	333.0	[0..6]	[230..70]
gi\|125807343, gi... - gi\|54635541\|gb\|EAL24944.1\| GA22088 [Drosophila pseudoobscura pseudoobscura], gi\|125807343\|ref\|XP_001... gi\|125807343\|ref... - GA22088-PA [Drosophila pseudoobscura], GA22088 [Drosophila pseudoobscura pseudoobscura] gi\|195149788, gi... - gi\|195149788\|ref\|XP_002015837.1\| GL11271 [Drosophila persimilis], gi\|194109684\|gb\|EDW31727.1\| GL1127...	333.0	[0..6]	[230..115]
ENSPTRT00000066622 - null gi\|80474966 - gi\|80474966\|gb\|AAI09055.1\| TBP protein [Homo sapiens] gi\|190691993, gi... - gi\|254071353\|gb\|ACT64436.1\| TATA box binding protein protein [synthetic construct], gi\|190691993\|gb\|...	333.0	[0..8]	[230..63]
gi\|109073361 - gi\|109073361\|ref\|XP_001085250.1\| PREDICTED: similar to TATA-box-binding protein (TATA-box factor) (T...	332.0	[0..8]	[230..63]
TBP_XENLA - TATA-box-binding protein OS=Xenopus laevis GN=tbp PE=1 SV=1	332.0	[0..6]	[230..70]
gi\|54696180 - gi\|54696180\|gb\|AAV38462.1\| TATA box binding protein [synthetic construct]	332.0	[0..8]	[230..111]
TBP_CHICK - TATA-box-binding protein OS=Gallus gallus GN=TBP PE=2 SV=1	332.0	[0..8]	[230..77]

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Predicted Domain #1

Region A:
Residues: [1-231]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFALPTTAS QASAFMNNSS LTFPVLPNAN NEATNETADS GDAEVSKNEG VSGIVPTLQN  60
   61 IVATVNLDCR LDLKTIALHA RNAEYNPKRF AAVIMRIREP KSTALIFASG KMVVLGGKSE 120
  121 DDSKLASRKY ARIIQKLGFN AKFTDFKIQN IVGSCDVKFP IRLEGLAYSH GTFSSYEPEL 180
  181 FPGLIYRMVK PKVVLLIFVS GKIVLTGAKV REEIYQAFEA IYPVLSEFRK H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.522879
Match:	1rm1A
Description:	Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
general RNA polymerase II transcription factor activity	10.1927670598446	bayes_pls_golite062009
RNA polymerase III transcription factor activity	8.4318102330583	bayes_pls_golite062009
transcription regulator activity	4.66773099672992	bayes_pls_golite062009
RNA polymerase II transcription factor activity	3.97397050058114	bayes_pls_golite062009
DNA binding	3.68758425895596	bayes_pls_golite062009
nucleic acid binding	3.4119217152884	bayes_pls_golite062009
binding	3.25203283623613	bayes_pls_golite062009
RNA polymerase I transcription factor activity	3.24777019705869	bayes_pls_golite062009
transcription factor activity	2.17821704710246	bayes_pls_golite062009
transcription factor binding	1.86204668268867	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.59579825271822	bayes_pls_golite062009
protein binding	0.938536348073543	bayes_pls_golite062009
transcription coactivator activity	0.312991469396539	bayes_pls_golite062009
transcription activator activity	0.199341831249925	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: