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View Structure Prediction Details

Protein: SPAC29E6.06c
Organism: Schizosaccharomyces pombe
Length: 754 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC29E6.06c.

Description E-value Query
Range
Subject
Range
gi|26328991, gi|... - gi|31980754|ref|NP_038770.2| cysteinyl-tRNA synthetase [Mus musculus], gi|26328991|dbj|BAC28234.1| u...
404.0 [0..5] [751..95]
gi|11191800 - gi|11191800|emb|CAC16398.1| Cysteinyl-tRNA-synthetase [Mus musculus domesticus]
gi|148686272 - gi|148686272|gb|EDL18219.1| cysteinyl-tRNA synthetase, isoform CRA_a [Mus musculus]
393.0 [0..5] [751..95]
gi|109105037 - gi|109105037|ref|XP_001096302.1| PREDICTED: similar to cysteinyl-tRNA synthetase isoform c isoform 4...
390.0 [0..5] [751..95]
gi|73982653 - gi|73982653|ref|XP_851224.1| PREDICTED: similar to cysteinyl-tRNA synthetase isoform c isoform 2 [Ca...
390.0 [0..8] [751..98]
gi|194380236, gi... - gi|62240992|ref|NP_001014437.1| cysteinyl-tRNA synthetase isoform c [Homo sapiens], gi|57997552|emb|...
389.0 [0..5] [751..95]
gi|114635634 - gi|114635634|ref|XP_001156119.1| PREDICTED: cysteinyl-tRNA synthetase isoform 6 [Pan troglodytes]
388.0 [0..5] [751..95]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTRNPAQSH WGVPKGQRTE LYVYNTLTHS KVPFVSNGSN LTWYCCGPTV YDASHMGHAR  60
   61 NYVTTDILRR ILQSYFGYNI TFVQNVTDID DKIILRARQQ YLFEEYKKQQ GT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.045757
Match: 1iq0A
Description: Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [113-636]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKSHSEAREK VTEAWFAYAK KNLPEPPSSM SEWPQWLASH DIPTLAINNP KLPMHVDALK  60
   61 SALDALQVSE ASEIISLDGF WPKVQDVLVP LLDAELGSTV TDPAIFRKLA AYWEDDFNKD 120
  121 MANLNVLPPT AVTRVSEYVP EIVDFVQRII DRGYAYPVTD GSVYFDTEAF EKGGHFYAKL 180
  181 EPWNKGNREL IAEGEGSLAA LTGKKRPGDF ALWKASKPGE PSWDSPWSKG RPGWHIECSV 240
  241 MASALLGSNI DIHSGGIDLA FPHHDNELAQ SEAYFDCPQW VNYFFHAGHL HIEGQKMSKS 300
  301 LKNFITIKEI LKKFTPRQLR LAFLLQQWNT QLDFKETLLA YVLNIEQALE NFFRTVRALM 360
  361 NETEGVSANG GHVPEKFDKL EIELLEKFQQ TQQNTHLALC DSFNTPLVMQ HIDNLVTQAN 420
  421 IYIREVGQQP CSRLLGQIAS WITSMLQIFG LDENGHPNAV GWSSSKGSSS ENTDAMPYIR 480
  481 AVSSFRDRVR ELCIAKASSQ EILKACDIFR DYDMAALGVS FNDR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.09691
Match: 1li5A
Description: Cysteinyl-tRNA synthetase (CysRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming aminoacyl-tRNA and related compounds 7.16276509815667 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.16276509815667 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.13957775963187 bayes_pls_golite062009
ligase activity 6.11211476973434 bayes_pls_golite062009
cysteine-tRNA ligase activity 5.23703961447809 bayes_pls_golite062009
isoleucine-tRNA ligase activity 3.76808520367507 bayes_pls_golite062009
glutamate-tRNA ligase activity 2.63681738794687 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
methionine-tRNA ligase activity 2.01261843164558 bayes_pls_golite062009
tyrosine-tRNA ligase activity 1.88984817882585 bayes_pls_golite062009
tryptophan-tRNA ligase activity 1.14187887833901 bayes_pls_golite062009
arginine-tRNA ligase activity 1.13743634264647 bayes_pls_golite062009
nucleotidyltransferase activity 0.89131347796645 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.625793556381714 bayes_pls_golite062009
nucleic acid binding 0.369886886936128 bayes_pls_golite062009
RNA binding 0.306683553109855 bayes_pls_golite062009
glutamine-tRNA ligase activity 0.118292082006187 bayes_pls_golite062009
binding 0.090743795600025 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [637-754]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQGSALVKLV DAEELIAARE QKLEEERAKQ AKKAQAKAEQ EKKQVERVMK GKTSPSEMFK  60
   61 MFKEYLSFDE AGLPTKMRGE DGSEIDVPKS RKKKLQKEYA QQEKLHKEYL SYIESNKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle