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View Structure Prediction Details

Protein: spo6
Organism: Schizosaccharomyces pombe
Length: 474 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for spo6.

Description E-value Query
Range
Subject
Range
HIM1_SCHPO - Hsk1-interacting molecule 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=him1 PE=1 SV=1
dfp1 - Hsk1-Dfp1 kinase complex regulatory subunit Dfp1
486.0 [0..44] [472..63]
gi|45200892, gi|... - gi|45200892|ref|NP_986462.1| AGL205Cp [Ashbya gossypii ATCC 10895], gi|44985662|gb|AAS54286.1| AGL20...
gi|44985662 - gi|44985662|gb|AAS54286.1| AGL205Cp [Ashbya gossypii ATCC 10895]
460.0 [0..11] [468..21]
gi|3643 - gi|3643|emb|CAA42819.1| cdc7 protein kinase subunit [Saccharomyces cerevisiae]
448.0 [0..12] [430..9]
gi|4102636 - gi|4102636|gb|AAD01519.1| G1/S regulator [Aspergillus nidulans]
417.0 [0..10] [474..53]
gi|49088112, gi|... - gi|67522645|ref|XP_659383.1| hypothetical protein AN1779.2 [Aspergillus nidulans FGSC A4], ref|XP_40...
414.0 [0..10] [474..38]
gi|76573716 - gi|76573716|dbj|BAE44800.1| hypothetical protein [Candida albicans]
gi|46438610, gi|... - gi|77022918|ref|XP_888903.1| hypothetical protein CaO19_5166 [Candida albicans SC5314], gi|68478104|...
397.0 [0..98] [468..75]
gi|169769266 - gi|169769266|ref|XP_001819103.1| hypothetical protein [Aspergillus oryzae RIB40]
gi|83766961 - gi|83766961|dbj|BAE57101.1| unnamed protein product [Aspergillus oryzae]
288.0 [0..10] [465..53]
gi|66848439, gi|... - gi|70991915|ref|XP_750806.1| G1/S regulator NimO [Aspergillus fumigatus Af293], gi|66848439|gb|EAL88...
286.0 [0..10] [452..38]
gi|115400531, gi... - gi|115400531|ref|XP_001215854.1| hypothetical protein ATEG_06676 [Aspergillus terreus NIH2624], gi|1...
282.0 [0..11] [446..38]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFYSVKSQP FVRSPLVDQN PSIQNINEEV KRDIQNPLSY KTETSDKELC QTAACATSCS  60
   61 DWYPQQQTHM PHQNAFDSAK ATAKMALPPT AFSNYCVKPS LTR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKDIPRTSIR VSKLRYWQRD YRLAFPNFIF YFDNVDEEIK RRVTQKINNL GAKVATLFTF  60
   61 EVTHFITTRT TDPEMCQPND VLYLSKTANM KIWLLDKLLN RILFTLLNSD SLVNTSASCL 120
  121 QSLLDGEKVY GT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.53
Match: 1wf6A
Description: The third BRCA1 C-terminus (BRCT) domain of Similar to S.pombe rad4+/cut5+ product
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.35986940498978 bayes_pls_golite062009
nucleic acid binding 1.23726848385925 bayes_pls_golite062009
DNA binding 1.21803358548345 bayes_pls_golite062009
protein binding 1.17425096415314 bayes_pls_golite062009
transcription regulator activity 0.948550635369826 bayes_pls_golite062009
damaged DNA binding 0.573570505312825 bayes_pls_golite062009
sequence-specific DNA binding 0.253994205417832 bayes_pls_golite062009
catalytic activity 0.201193336576136 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [236-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDKDFYVPSK NVEYFREYFL CIRDLSQYYK PIAVREWEKT LDSGEILWPS LAITAQGRCP  60
   61 FNTGRRRELK ITKHNHPAHE IRKQLLSCTN QTNQNNVVKN SASVLVRQIM GDYNITESAV 120
  121 DGAKQMP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.205 a.74.1 Cyclin-like

Predicted Domain #4
Region A:
Residues: [363-474]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEFPKPENLL PVEKRAAMSP LNLLEPRLIN KQNTLANQSP RQPPNAFDAD PLAHKKVKIE  60
   61 TKSGYCENCC ERYKDLERHL GGKHHRRFAE KDENFQGLDD LFLLIRRPIR TN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle