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View Structure Prediction Details

Protein: rpn7
Organism: Schizosaccharomyces pombe
Length: 409 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpn7.

Description E-value Query
Range
Subject
Range
gi|114587651 - gi|114587651|ref|XP_520898.2| PREDICTED: proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 ...
305.0 [0..10] [403..222]
gi|12845617 - gi|12845617|dbj|BAB26823.1| unnamed protein product [Mus musculus]
295.0 [0..10] [403..4]
gi|149040032, gi... - gi|38454206|ref|NP_942025.1| proteasome, 26S, non-ATPase regulatory subunit 6 [Rattus norvegicus], g...
294.0 [0..10] [403..4]
gi|208965390 - gi|208965390|dbj|BAG72709.1| proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 [synthetic c...
ENSPTRT00000028219 - null
PSMD6 - proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
294.0 [0..10] [403..4]
PSMD6_BOVIN - 26S proteasome non-ATPase regulatory subunit 6 OS=Bos taurus GN=PSMD6 PE=2 SV=1
293.0 [0..10] [403..4]
AGAP002061-PA - 26S proteasome regulatory subunit N7|protein_coding|2R:14716192:14717361:1|gene:AGAP002061
gi|58395080, gi|... - gi|58395080|ref|XP_320986.2| AGAP002061-PA [Anopheles gambiae str. PEST], gi|55233320|gb|EAA01099.3|...
293.0 [0..10] [403..4]
gi|109037701 - gi|109037701|ref|XP_001093028.1| PREDICTED: proteasome (prosome, macropain) 26S subunit, non-ATPase,...
gi|90074922 - gi|90074922|dbj|BAE87141.1| unnamed protein product [Macaca fascicularis]
293.0 [0..10] [403..4]
gi|73985103 - gi|73985103|ref|XP_541816.2| PREDICTED: similar to 26S proteasome non-ATPase regulatory subunit 6 (2...
292.0 [0..10] [403..4]
gi|27694784, gi|... - gi|27694784|gb|AAH43825.1| P44s10-prov protein [Xenopus laevis], gi|147904380|ref|NP_001080462.1| hy...
289.0 [0..10] [403..4]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCSPSATLTH RTMTEKARTV SDLTISQAIF ELSSPFLENK SQKALDTLFS AIRDHDLAPL  60
   61 YKYLSENPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [70-299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSASIDFDSN FLNSMIKKNE EKLAEFDKAI EDAQELNGEH EILEAMKNKA DYYTNICDRE  60
   61 RGVQLCDETF ERATLTGMKI DVLFSKIRLA YVYADMRVVG QLLEKLKPLI EKGGDWERKN 120
  121 RLKAYQGIYL MSIRNFSGAA DLLLDCMSTF SSTELLPYYD VVRYAVISGA ISLDRVDVKT 180
  181 KIVDSPEVLA VLPQNESMSS LEACINSLYL CDYSGFFRTL ADVEVNHLKC 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.522879
Match: 2fo7A
Description: Crystal structure of an 8 repeat consensus TPR superhelix (trigonal crystal form)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [300-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DQFLVAHYRY YVREMRRRAY AQLLESYRAL SIDSMAASFG VSVDYIDRDL ASFIPDNKLN  60
   61 CVIDRVNGVV FTNRPDEKNR QYQEVVKQGD VLLNKLQKYQ ATVMRGAFKV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.50995556050336 bayes_pls_golite062009
nucleic acid binding 3.38144578566524 bayes_pls_golite062009
binding 3.33026160538031 bayes_pls_golite062009
DNA binding 3.30822066787723 bayes_pls_golite062009
transcription factor activity 2.60537570879007 bayes_pls_golite062009
hydrolase activity 2.30467124306022 bayes_pls_golite062009
sequence-specific DNA binding 1.32971938164691 bayes_pls_golite062009
transcription activator activity 1.08566311616647 bayes_pls_golite062009
transcription repressor activity 0.95491822926452 bayes_pls_golite062009
protein binding 0.653872239015235 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.505349137311395 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.42135864069093 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.136726704233672 bayes_pls_golite062009
small conjugating protein ligase activity 0.118016217031359 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle