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View Structure Prediction Details

Protein: res2
Organism: Schizosaccharomyces pombe
Length: 657 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for res2.

Description E-value Query
Range
Subject
Range
gi|73952670 - gi|73952670|ref|XP_536358.2| PREDICTED: similar to ankyrin 3 isoform 1 isoform 1 [Canis familiaris]
434.0 [0..7] [650..77]
gi|57162615, gi|... - gi|57209239|emb|CAI41373.1| ankyrin 3, node of Ranvier (ankyrin G) [Homo sapiens], gi|57162615|emb|C...
433.0 [0..7] [650..77]
gi|66847484, gi|... - gi|70990006|ref|XP_749852.1| Pfs, NACHT and Ankyrin domain protein [Aspergillus fumigatus Af293], gi...
432.0 [0..3] [595..930]
gi|109467596 - gi|109467596|ref|XP_001076082.1| PREDICTED: similar to ankyrin 2 isoform 1 [Rattus norvegicus]
428.0 [0..7] [652..67]
gi|109075425 - gi|109075425|ref|XP_001095471.1| PREDICTED: ankyrin 2, neuronal isoform 12 [Macaca mulatta]
427.0 [0..7] [652..67]
gi|108868779, gi... - gi|157106769|ref|XP_001649474.1| ankyrin 2,3/unc44 [Aedes aegypti], gi|108868779|gb|EAT33004.1| anky...
427.0 [0..4] [652..19]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPRSSAVHV AVYSGVEVYE CFIKGVSVMR RRRDSWLNAT QILKVADFDK PQRTRVLERQ  60
   61 VQIGAHEKVQ GGYGKYQGTW VPFQRGVDLA TKYKVDGIMS PILSLDIDEG KAIAPKKKQT 120
  121 KQKKPSVRGR RGRKPSSLSS STLHSVNEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.39794
Match: 1mb1A
Description: MBP1 FROM SACCHAROMYCES CEREVISIAE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.36949648004482 bayes_pls_golite062009
DNA binding 4.06494205639151 bayes_pls_golite062009
nucleic acid binding 3.98559547948274 bayes_pls_golite062009
transcription factor activity 3.87642218322379 bayes_pls_golite062009
binding 2.79149251200147 bayes_pls_golite062009
sequence-specific DNA binding 2.09766190372909 bayes_pls_golite062009
transcription repressor activity 0.838109968340069 bayes_pls_golite062009
protein binding 0.504276536503861 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [150-657]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPNSSISPTI ESSMNKVNLP GAEEQVSATP LPASPNALLS PNDNTIKPVE ELGMLEAPLD  60
   61 KYEESLLDFF LHPEEGRIPS FLYSPPPDFQ VNSVIDDDGH TSLHWACSMG HIEMIKLLLR 120
  121 ANADIGVCNR LSQTPLMRSV IFTNNYDCQT FGQVLELLQS TIYAVDTNGQ SIFHHIVQST 180
  181 STPSKVAAAK YYLDCILEKL ISIQPFENVV RLVNLQDSNG DTSLLIAARN GAMDCVNSLL 240
  241 SYNANPSIPN RQRRTASEYL LEADKKPHSL LQSNSNASHS AFSFSGISPA IISPSCSSHA 300
  301 FVKAIPSISS KFSQLAEEYE SQLREKEEDL IRANRLKQDT LNEISRTYQE LTFLQKNNPT 360
  361 YSQSMENLIR EAQETYQQLS KRLLIWLEAR QIFDLERSLK PHTSLSISFP SDFLKKEDGL 420
  421 SLNNDFKKPA CNNVTNSDEY EQLINKLTSL QASRKKDTLY IRKLYEELGI DDTVNSYRRL 480
  481 IAMSCGINPE DLSLEILDAV EEALTREK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.09691
Match: 1n11A
Description: Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.60916417202222 bayes_pls_golite062009
transcription regulator activity 2.37103377984038 bayes_pls_golite062009
nucleic acid binding 1.8957142857582 bayes_pls_golite062009
DNA binding 1.78305438715057 bayes_pls_golite062009
protein binding 1.64872738860757 bayes_pls_golite062009
transcription factor activity 1.2667825651547 bayes_pls_golite062009
transcription factor binding 1.06366405671195 bayes_pls_golite062009
cytoskeletal protein binding 0.56201598804914 bayes_pls_golite062009
transcription activator activity 0.312682802870618 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 0.0462605323512499 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle