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View Structure Prediction Details

Protein: SPBC4C3.10c
Organism: Schizosaccharomyces pombe
Length: 226 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC4C3.10c.

Description E-value Query
Range		 Subject
Range
PSA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=psmA PE=3 SV=1
PSMA_PYRAB - Proteasome subunit alpha OS=Pyrococcus abyssi GN=psmA PE=3 SV=1
 223.0 [0..1] [221..14]
PSA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=p...
PSMA_PYRFU - Proteasome subunit alpha OS=Pyrococcus furiosus GN=psmA PE=3 SV=1
 221.0 [0..1] [221..14]
PSA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC ...
PSMA_PYRHO - Proteasome subunit alpha OS=Pyrococcus horikoshii GN=psmA PE=3 SV=1
 221.0 [0..1] [221..14]
PSA_THEK1 - Proteasome subunit alpha OS=Thermococcus sp. (strain JCM 11816 / KS-1) GN=psmA PE=3 SV=1
PSA_THEK1, PSMA_... - Proteasome subunit alpha OS=Thermococcus sp. (strain KS-1) GN=psmA PE=3 SV=1, Proteasome subunit alp...
gi|11265988 - pir||T43887 proteasome alpha chain [imported] - Thermococcus sp
 214.0 [0..1] [224..14]
PSMA_PYRKO - Proteasome subunit alpha OS=Pyrococcus kodakaraensis GN=psmA PE=3 SV=1
PSA_THEKO - Proteasome subunit alpha OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) GN=ps...
 213.0 [0..1] [224..14]
PSA4_SPIOL - Proteasome subunit alpha type-4 OS=Spinacia oleracea GN=PAC1 PE=2 SV=1
 213.0 [0..2] [203..10]
gi|6984140 - gi|6984140|gb|AAF34770.1|AF227625_1 proteasome 27 kDa subunit [Euphorbia esula]
 212.0 [0..2] [203..2]
gi|77999303 - gi|77999303|gb|ABB16998.1| proteasome-like protein alpha subunit [Solanum tuberosum]
 210.0 [0..2] [203..10]
gi|111058979 - gi|111058979|gb|EAT80099.1| hypothetical protein SNOG_12286 [Phaeosphaeria nodorum SN15]
 210.0 [0..2] [224..10]

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Predicted Domain #1
Region A:
Residues: [1-226] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTVKDTMN VDINAIKKGE IRMGTTITAL RYKDGVILAA DSRTTMGAYI ANRVTDKLTQ  60
   61 LTDNIWCCRS GSAADTQTVA DLLKYYLSMY RIQFGHDPSV HTAATLASEM CYQNKNMLSA 120
  121 GLIVAGYDEK TGGDVYSIPL GGSLHKQPLA IGGSGSAFIY GFCDANFREN MTQEEAVEFL 180
  181 KNAVALAMER DGSSGGTIRM VILNKDGMER KFFAIDTANP IPVFTH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.69897
Match: 1iruH
Description: Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endopeptidase activity 6.91642761177919 bayes_pls_golite062009
peptidase activity 6.84511694091156 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.5973571808298 bayes_pls_golite062009
hydrolase activity 4.47652590304822 bayes_pls_golite062009
threonine-type endopeptidase activity 2.98214579292788 bayes_pls_golite062009
threonine-type peptidase activity 2.98214579292788 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009
binding 1.18139971903068 bayes_pls_golite062009
nucleic acid binding 0.448212653390607 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle