YRC Public Data Repository - Protein Structure Prediction

Protein:	gut2
Organism:	Schizosaccharomyces pombe
Length:	649 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gut2.

Description	E-value	Query Range	Subject Range
gi\|46437136, gi\|... - gi\|68481335\|ref\|XP_715442.1\| hypothetical protein CaO19.3133 [Candida albicans SC5314], gi\|68481194\|... gi\|238881220 - gi\|238881220\|gb\|EEQ44858.1\| glycerol-3-phosphate dehydrogenase, mitochondrial precursor [Candida alb... orf19.10645, orf... - GUT2 CGDID:CAL0002288 Assembly 19, Contig19-10166 (96169, 94217) CDS, reverse complemented, translat...	411.0	[0..1]	[649..1]
Gpo-1-PD, Gpo-1-... - The gene Glycerophosphate oxidase-1 is referred to in FlyBase by the symbol Dmel\Gpo-1 (CG8256, FBgn... gi\|220954864, gi... - gi\|220954864\|gb\|ACL89975.1\| Gpo-1-PA [synthetic construct], gi\|220945030\|gb\|ACL85058.1\| Gpo-1-PA [sy...	366.0	[0..4]	[649..1]
gi\|125812000\|ref... - GA20935-PA [Drosophila pseudoobscura], GA20935 [Drosophila pseudoobscura pseudoobscura] gi\|125812000, gi... - gi\|54637252\|gb\|EAL26655.1\| GA20935 [Drosophila pseudoobscura pseudoobscura], gi\|125812000\|ref\|XP_001... gi\|195171751, gi... - gi\|195171751\|ref\|XP_002026667.1\| GL11848 [Drosophila persimilis], gi\|194111593\|gb\|EDW33636.1\| GL1184...	365.0	[0..4]	[649..1]
gi\|49655350 - gi\|49655350\|emb\|CAG87918.1\| DEHA2E08624p [Debaryomyces hansenii] gi\|49655350, gi\|... - gi\|50422239\|ref\|XP_459682.1\| hypothetical protein DEHA0E09163g [Debaryomyces hansenii CBS767], gi\|49...	363.0	[0..29]	[649..29]
gi\|44984842, gi\|... - gi\|45198813\|ref\|NP_985842.1\| AFR295Wp [Ashbya gossypii ATCC 10895], gi\|44984842\|gb\|AAS53666.1\| AFR29... gi\|44984842 - gi\|44984842\|gb\|AAS53666.1\| AFR295Wp [Ashbya gossypii ATCC 10895]	361.0	[0..1]	[636..1]
GPD2 - glycerol-3-phosphate dehydrogenase 2 (mitochondrial)	359.0	[0..6]	[631..8]
gi\|51013185 - gi\|51013185\|gb\|AAT92886.1\| YIL155C [Saccharomyces cerevisiae]	359.0	[0..24]	[636..24]
h0014824 - null GPD2 - glycerol-3-phosphate dehydrogenase 2 (mitochondrial) gi\|114581287, gi... - gi\|114581291\|ref\|XP_001143123.1\| PREDICTED: glycerol-3-phosphate dehydrogenase 2 (mitochondrial) iso...	359.0	[0..6]	[631..8]

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Predicted Domain #1

Region A:
Residues: [1-63]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSIFKRRSV QAALAASGLV GGAVFYSDFI KRPAPSHFNP QFTPFTKSLA PPPSRETLLK  60
   61 NVE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.0
Match:	1ps9A
Description:	The Crystal Structure and Reaction Mechanism of E. coli 2,4-Dienoyl CoA Reductase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [64-555]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DISKFDVLII GGGATGTGVA VDASTRGLNV CLLEKTDFAS ETSSKSTKMA HGGVRYLEKA  60
   61 VFQLSKAQLD LVIEALNERA NMLRTAPHLC TVLPIMIPVY KWWQVPYFFV GCKIYDWVAG 120
  121 SKNLRASTIF SKETTVAIAP MLDDSNLKAS CVYHDGSFND TRMNTTLAVT AIDNGATVLN 180
  181 YMEVKKLLKS KDNKLEGVLA IDRETGKEYQ IKATSVVNAT GPFSDKILEM DADPQGEPPK 240
  241 TAQFPRMVVP SAGVHVVLPE YYCPPNIGIL DPSTSDNRVM FFLPWQGKVI AGTTDKPLSS 300
  301 VPTNPTPSED DIQLILKELQ KYLVFPVDRE DVLSAWCGIR PLVRDPSTVP PGTDPTTGET 360
  361 QGLVRSHFIF KSDTGLLTIS GGKWTTYREM AEETVNELIK DHDFGKALKP CQTKKLILVG 420
  421 GENYYKNYSA RLIHEYHIPL RLAKHLSHNY GSRAPLILEL YSKTDFNKLP VTLADKEVFA 480
  481 PSSDASSDKS VS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.522879
Match:	1chuA
Description:	L-aspartate oxidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on NADH or NADPH	5.26950448055146	bayes_pls_golite062009
succinate dehydrogenase (ubiquinone) activity	5.14102850576304	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	5.14102850576304	bayes_pls_golite062009
succinate dehydrogenase activity	5.05915186333685	bayes_pls_golite062009
oxidoreductase activity	3.25470541847124	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	3.13549066533631	bayes_pls_golite062009
L-aspartate oxidase activity	2.98036603638887	bayes_pls_golite062009
aspartate oxidase activity	2.16464783424214	bayes_pls_golite062009
catalytic activity	1.75556359035561	bayes_pls_golite062009
electron carrier activity	1.6933266990239	bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity	1.59912481901166	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.45104542724719	bayes_pls_golite062009
transporter activity	1.29839290134235	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.18990628739838	bayes_pls_golite062009
antioxidant activity	1.12347155061135	bayes_pls_golite062009
transmembrane transporter activity	1.07862908893913	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	0.932244769173724	bayes_pls_golite062009
substrate-specific transporter activity	0.811783414198063	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	0.798505263716232	bayes_pls_golite062009
binding	0.746779212723453	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.69501605197281	bayes_pls_golite062009
NADPH-adrenodoxin reductase activity	0.573803337547311	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.55964362614766	bayes_pls_golite062009
FAD binding	0.503028015880333	bayes_pls_golite062009
pyruvate dehydrogenase activity	0.494423552127166	bayes_pls_golite062009
protein binding	0.281967023349804	bayes_pls_golite062009
ion transmembrane transporter activity	0.262741975112034	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	0.224438371728402	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.164825358655637	bayes_pls_golite062009
coenzyme binding	0.162431069593696	bayes_pls_golite062009
cation transmembrane transporter activity	0.057221373695437	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [556-649]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YASFDEPFTV AELKYSIKYE YTRTPTDFLA RRTRLAFLDA RQALQAVAGV THVMKEEFGW  60
   61 DDATTDKLAQ EARDYIGGMG VSSDRFDVKQ FEVK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.920	0.123	glycerol-3-phosphate metabolic process	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: