Protein Overview: Gpo-1-PD, Gpo-1-...

General Information:
Name(s) found:	Gpo-1-PD / FBpp0111813 [FlyBase] Gpo-1-PA / FBpp0086444 [FlyBase] Gpo-1-PB / FBpp0086443 [FlyBase] Gpo-1-PC / FBpp0086442 [FlyBase]
Description(s) found: Found 61 descriptions. SHOW ALL	The gene Glycerophosphate oxidase-1 is referred to in FlyBase by the symbol Dmel\Gpo-1 (CG8256, FBgn0022160). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11745256..11750251. It has the cytological map location 52C8. There is experimental evidence that it has the molecular function</span>: glycerol-3-phosphate dehydrogenase activity. There is experimental evidence that it is involved in the biological process</span>: glycerophosphate shuttle; flight behavior. 16 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Glycerophosphate oxidase-1 is referred to in FlyBase by the symbol Dmel\Gpo-1 (CG8256, FBgn0022160). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11745256..11750251. It has the cytological map location 52C8. There is experimental evidence that it has the molecular function</span>: glycerol-3-phosphate dehydrogenase activity. There is experimental evidence that it is involved in the biological process</span>: glycerophosphate shuttle; flight behavior. 16 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Glycerophosphate oxidase-1 is referred to in FlyBase by the symbol Dmel\Gpo-1 (CG8256, FBgn0022160). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11745256..11750251. It has the cytological map location 52C8. There is experimental evidence that it has the molecular function</span>: glycerol-3-phosphate dehydrogenase activity. There is experimental evidence that it is involved in the biological process</span>: glycerophosphate shuttle; flight behavior. 16 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene Glycerophosphate oxidase-1 is referred to in FlyBase by the symbol Dmel\Gpo-1 (CG8256, FBgn0022160). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11745256..11750251. It has the cytological map location 52C8. There is experimental evidence that it has the molecular function</span>: glycerol-3-phosphate dehydrogenase activity. There is experimental evidence that it is involved in the biological process</span>: glycerophosphate shuttle; flight behavior. 16 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	724 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA] glycerol-3-phosphate dehydrogenase complex [IEA] mitochondrion [IC][ISS] mitochondrial inner membrane [IDA]
Biological Process:	glycerol metabolic process [ISS] glycerol-3-phosphate metabolic process [IEA] flight behavior [IMP] glycerophosphate shuttle [IMP]
Molecular Function:	calcium ion binding [IEA] glycerol-3-phosphate dehydrogenase activity [IMP][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSRMFKFGV TAASACVGSV LASYTLDRWN TPHVVNNATV PPKRKRTLPP RADQIKSLMS  60
   61 GEEFDVLIIG GGATGAGCAL DSVTRGLKTA LVELDDFASG TSSRSTKLIH GGVRYLQKAI 120
  121 LGLDLEQYRM VKEALAERAT MLESAPHLTH PLPIMLPVYT WWQVPYYWVG IKAYDLVAGD 180
  181 RNVKSSYYLS KKDALELFPM LKKDKLCGAI VYYDGQQDDA RMCLAVALTA ARHGATVCNH 240
  241 VEVKELLKKD DGTGKQVLCG AKVKDHISGK EFTVKAKCIV NAAGPFTDSI RKMDNPTVKS 300
  301 ICCPSSGVHI VLPGYYSPDQ MGLLDPSTSD GRVIFFLPWQ RQTIAGTTDL PCEITHNPTP 360
  361 TEDEIQFILN EIKNYLNADV EVRRGDVLSA WSGIRPLVSD PNKDDTQSLA RNHIVHVSPS 420
  421 NLITIAGGKW TTYRAMAEHT IDAAIKACNL KPERAEAVTS YLKIEGGQGW TPTMYIRLVQ 480
  481 DFGLECEVAQ HLAKSYGDRA FAVSKMASLT GKRWPIIGNR IHPEFPYIDA EIRYGVREYA 540
  541 CTAVDMIARR LRLAFLNVQA AQEALPVIVD IMGEELGWSK DEKERQIKHA TEFLANEMGH 600
  601 SVNRTSKERI PIKLSKEEIQ TYIKRFQLID KDKKGYVSIN DIRRALKSFG DGDVSGEQLH 660
  661 EILREIDTNM NGQVELDEYL QMMSAIKTGD VAYSRFARMA ELEEQKHEAA NLKQISVDRS 720
  721 GGGL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

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Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
oxidoreductase activity, acting on NADH or NADPH	5.26950448055146	bayes_pls_golite062009
oxidoreductase activity	2.3417445147889	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	2.25002926602325	bayes_pls_golite062009
electron-transferring-flavoprotein dehydrogenase activity	1.55451764082771	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.45104542724719	bayes_pls_golite062009
transporter activity	1.29839290134235	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.18990628739838	bayes_pls_golite062009
antioxidant activity	1.12347155061135	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1.08975609376408	bayes_pls_golite062009
transmembrane transporter activity	1.07862908893913	bayes_pls_golite062009
catalytic activity	1.03127962968326	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	0.955909900559292	bayes_pls_golite062009
binding	0.850689563354756	bayes_pls_golite062009
substrate-specific transporter activity	0.811783414198063	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.69501605197281	bayes_pls_golite062009
NADPH-adrenodoxin reductase activity	0.573803337547311	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.55964362614766	bayes_pls_golite062009
pyruvate dehydrogenase activity	0.494423552127166	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH group of donors	0.442625746935807	bayes_pls_golite062009
protein binding	0.370064403093958	bayes_pls_golite062009
ion transmembrane transporter activity	0.262741975112034	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	0.224438371728402	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.164825358655637	bayes_pls_golite062009
nucleic acid binding	0.162130833238942	bayes_pls_golite062009
amine oxidase activity	0.0576694782267841	bayes_pls_golite062009
cation transmembrane transporter activity	0.057221373695437	bayes_pls_golite062009
DNA binding	0.022476246602636	bayes_pls_golite062009

Term	Confidence	Notes
binding	2.30946149202257	bayes_pls_golite062009
protein binding	1.18539140568889	bayes_pls_golite062009
transporter activity	1.15928534291452	bayes_pls_golite062009
calcium ion binding	1.03474411638676	bayes_pls_golite062009
transmembrane transporter activity	0.945691505472547	bayes_pls_golite062009
ion binding	0.882500417315612	bayes_pls_golite062009
cation binding	0.87665890173512	bayes_pls_golite062009
metal ion binding	0.87665890173512	bayes_pls_golite062009
substrate-specific transporter activity	0.693724160233023	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.45412801027969	bayes_pls_golite062009
active transmembrane transporter activity	0.246383459363256	bayes_pls_golite062009
cytoskeletal protein binding	0.2350628837209	bayes_pls_golite062009
ion transmembrane transporter activity	0.193201281459889	bayes_pls_golite062009
motor activity	0.0886596083402598	bayes_pls_golite062009
cation transmembrane transporter activity	0.0305250212662123	bayes_pls_golite062009
molecular transducer activity	0.0215587845132821	bayes_pls_golite062009
signal transducer activity	0.0215587845132821	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..69]	PSI-BLAST	5.522879	Structure of N-Terminal FAD Binding motif of mouse MICAL
2	View Details	[70..551]	PSI-BLAST	34.522879	Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with acetate
3	View Details	[552..724]	PSI-BLAST	27.09691	Calmodulin

Protein Overview: Gpo-1-PD, Gpo-1-...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: