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View Structure Prediction Details

Protein: SPBC1271.04c
Organism: Schizosaccharomyces pombe
Length: 350 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC1271.04c.

Description E-value Query
Range
Subject
Range
gi|7490433 - gi|7490433|pir||T39340 deoxyhypusine synthase (EC 2.5.1.46) SPBC1271.04c [similarity] - fission yeas...
551.0 [0..1] [350..1]
DHPS - deoxyhypusine synthase
gi|190689417, gi... - gi|190690779|gb|ACE87164.1| deoxyhypusine synthase protein [synthetic construct], gi|190689417|gb|AC...
537.0 [0..3] [350..10]
DHYS_ARATH - Deoxyhypusine synthase OS=Arabidopsis thaliana GN=DHS PE=2 SV=1
535.0 [0..4] [349..8]
DHYS_RAT - Deoxyhypusine synthase OS=Rattus norvegicus GN=Dhps PE=2 SV=1
533.0 [0..3] [350..10]
DHYS_SENVE - Deoxyhypusine synthase OS=Senecio vernalis GN=DHS1 PE=2 SV=1
533.0 [0..7] [349..15]
DHYS_MOUSE - Deoxyhypusine synthase OS=Mus musculus GN=Dhps PE=1 SV=2
531.0 [0..3] [350..10]

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Predicted Domain #1
Region A:
Residues: [1-350]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDESLAKDAV FVASSKPSDL TTEVVGPDFN KYDERKKAGG PGITVEELVE SYGKIGFQAT  60
   61 NLHDAVTIIN EMRNWRDPNP PEEKSDRATI FLGYTSNLIS SGVREVLRYL VQHKCVDVIV 120
  121 TTAGGVEEDI IKCLGPTYVG DFHLDGKNLR AKGLNRIGNL IVPNDNYCRF EEWIFPILNK 180
  181 MVEEQETLGT HWTPSSFIRR LGKEINDESS VLYWAYKNNI PIYSPALTDG SIGDMLYFHT 240
  241 YKATPRPLVL DIVADIRNMN THAVRANKSG IIILGGGVVK HHICNANLMR NGAEWSVYIN 300
  301 SANEFDGSDA GARPDEAVSW GKIRGDAKKV KVYGEVSLLF PLIVAATFAK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 153.0
Match: 1dhsA
Description: CRYSTAL STRUCTURE OF THE NAD COMPLEX OF HUMAN DEOXYHYPUSINE SYNTHASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
deoxyhypusine synthase activity 4.8590235726137 bayes_pls_golite062009
transcription regulator activity 2.51117258094456 bayes_pls_golite062009
protein deacetylase activity 2.11398191156761 bayes_pls_golite062009
DNA binding 2.09930834951157 bayes_pls_golite062009
histone deacetylase activity 2.08718650273166 bayes_pls_golite062009
binding 2.06552694538163 bayes_pls_golite062009
nucleic acid binding 2.00972611627502 bayes_pls_golite062009
NAD-dependent protein deacetylase activity 1.93141177609772 bayes_pls_golite062009
NAD-dependent histone deacetylase activity 1.93141177609772 bayes_pls_golite062009
protein binding 1.52593340148652 bayes_pls_golite062009
deacetylase activity 1.15111805612466 bayes_pls_golite062009
transcription factor binding 1.07103864164531 bayes_pls_golite062009
transcription factor activity 1.0180828203704 bayes_pls_golite062009
catalytic activity 0.739210399081789 bayes_pls_golite062009
transcription repressor activity 0.516307124442946 bayes_pls_golite062009
transferase activity 0.483523935618287 bayes_pls_golite062009
transcription cofactor activity 0.42635585193838 bayes_pls_golite062009
transcription corepressor activity 0.23414654967509 bayes_pls_golite062009
hydrolase activity 0.169696911903799 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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