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View Structure Prediction Details

Protein: app1
Organism: Schizosaccharomyces pombe
Length: 857 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for app1.

Description E-value Query
Range
Subject
Range
gi|37930527, gi|... - gi|37930527|gb|AAP74661.1| elicitor-like transglutaminase M81 [Phytophthora infestans], gi|23505399|...
254.0 [0..61] [813..609]
SLAP1_CLOTH - Cell surface glycoprotein 1 OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 ...
236.0 [0..105] [761..1361]
FP1_MYTCO - Adhesive plaque matrix protein OS=Mytilus coruscus GN=FP1 PE=2 SV=1
228.0 [0..68] [749..181]
gi|70878103 - gi|70878103|gb|EAN91386.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71648919 - gi|71648919|ref|XP_813237.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
226.0 [0..59] [799..677]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
222.0 [0..105] [794..755]
FP1_MYTGA - Adhesive plaque matrix protein OS=Mytilus galloprovincialis GN=FP1 PE=2 SV=1
216.0 [0..94] [775..60]
gi|4322306 - gi|4322306|gb|AAD16007.1| ponsin-2 [Mus musculus]
208.0 [0..251] [857..22]
gi|78000171 - gi|78000171|ref|NP_001030129.1| sorbin and SH3 domain containing 1 isoform 7 [Homo sapiens]
208.0 [0..186] [857..9]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFQLDTSTH GAEIRNVYEK VLSGADDCSW AIFGYEKGQG NILKVVASGN DNDEFLDEFD  60
   61 ENAVLFGFLR VKDVNTGLNK FVLVCWCGEA AARKGLFSIH MATVSNLLKG YHVQITGRES 120
  121 SDLNMDDIIR RVADASGSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.522879
Match: 1x67A
Description: Solution structure of the cofilin homology domain of HIP-55 (drebrin-like protein)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [140-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSVHTSNSTP QSKHNAFYDA SQTFGSTAKV APAPAPSTKT PLANISKPVV QAQKDSKDNS  60
   61 WDDSSKQSNT QTANTTSNLR VPVNASWSDA GRKEKSQENK PKPTPFGSGG PSKPTPFESH 120
  121 GPAKQISVQP SEHPKPSIST TTTGS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.09
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #3
Region A:
Residues: [285-357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYRSAESSHA PTTPDHFKLT PLTKLEPQPP SGSPSKKPVS ELEELHTAGN VNLSARRALF  60
   61 EKKESSTKNV ENP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [358-487]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSHHLKSPVR TSFPPASTTA SKQDSPSTVP VDKQETAKPI NKQVSSNETS AQEEPRESVA  60
   61 ALRARFAKAN VSENNDPPTF PKTAAKISSF NSKAGTSFAK PRPFTNNPNP ISAPEKPTSG 120
  121 ESLSLNPPPA 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [488-634]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKVFPERDI SSASQKAAQP SVITPSVPQP PAAPVVPEAP SVHQPPAAPV APEVPSAPQR  60
   61 PAAPVVPEAP SVPQRPAVPV VPEALSVPQP PVAPVAPEVP SVPQPPVAPV VPEAPSVPQP 120
  121 PVAPVAPEVP SVPQRPAVPV VPEAPSV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [635-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQPPAAPVVP EVPSVPQRPA VPVVPEAPSV PQPPAAPVVP EVPSVPQPPA VPVVPEAGQL  60
   61 NEPVVPPLPP HDETQEPQVG GDVKATEHTQ PTKTPAIVIY DYS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [738-857]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEEENEIELV ENEQIQILEF VDDGWWLGEN SKGQQGLFPS NYVEITGPNE TANNPPAEPQ  60
   61 AGGPGKSVKA IYDYQAQEDN ELSFFEDEII ANVDCVDPNW WEGECHGHRG LFPSNYVEEI 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.09691
Match: 1uecA
Description: p47pox (neutrophil cytosolic factor 1)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle