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View Structure Prediction Details

Protein: app1
Organism: Schizosaccharomyces pombe
Length: 857 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for app1.

Description E-value Query
Range
Subject
Range
gi|37930527, gi|... - gi|37930527|gb|AAP74661.1| elicitor-like transglutaminase M81 [Phytophthora infestans], gi|23505399|...
254.0 [0..61] [813..609]
SLAP1_CLOTH - Cell surface glycoprotein 1 OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 ...
236.0 [0..105] [761..1361]
FP1_MYTCO - Adhesive plaque matrix protein OS=Mytilus coruscus GN=FP1 PE=2 SV=1
228.0 [0..68] [749..181]
gi|70878103 - gi|70878103|gb|EAN91386.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71648919 - gi|71648919|ref|XP_813237.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
226.0 [0..59] [799..677]
SLP1_CLOTM, SLAP... - (Q06852) Cell surface glycoprotein 1 precursor (Outer layer protein B) (S-layer protein 1), Cell sur...
222.0 [0..105] [794..755]
FP1_MYTGA - Adhesive plaque matrix protein OS=Mytilus galloprovincialis GN=FP1 PE=2 SV=1
216.0 [0..94] [775..60]
gi|4322306 - gi|4322306|gb|AAD16007.1| ponsin-2 [Mus musculus]
208.0 [0..251] [857..22]
gi|78000171 - gi|78000171|ref|NP_001030129.1| sorbin and SH3 domain containing 1 isoform 7 [Homo sapiens]
208.0 [0..186] [857..9]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFQLDTSTH GAEIRNVYEK VLSGADDCSW AIFGYEKGQG NILKVVASGN DNDEFLDEFD  60
   61 ENAVLFGFLR VKDVNTGLNK FVLVCWCGEA AARKGLFSIH MATVSNLLKG YHVQITGRES 120
  121 SDLNMDDIIR RVADASGSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.522879
Match: 1x67A
Description: Solution structure of the cofilin homology domain of HIP-55 (drebrin-like protein)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [140-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSVHTSNSTP QSKHNAFYDA SQTFGSTAKV APAPAPSTKT PLANISKPVV QAQKDSKDNS  60
   61 WDDSSKQSNT QTANTTSNLR VPVNASWSDA GRKEKSQENK PKPTPFGSGG PSKPTPFESH 120
  121 GPAKQISVQP SEHPKPSIST TTTGS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.09
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #3
Region A:
Residues: [285-357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYRSAESSHA PTTPDHFKLT PLTKLEPQPP SGSPSKKPVS ELEELHTAGN VNLSARRALF  60
   61 EKKESSTKNV ENP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [358-487]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSHHLKSPVR TSFPPASTTA SKQDSPSTVP VDKQETAKPI NKQVSSNETS AQEEPRESVA  60
   61 ALRARFAKAN VSENNDPPTF PKTAAKISSF NSKAGTSFAK PRPFTNNPNP ISAPEKPTSG 120
  121 ESLSLNPPPA 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [488-634]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKVFPERDI SSASQKAAQP SVITPSVPQP PAAPVVPEAP SVHQPPAAPV APEVPSAPQR  60
   61 PAAPVVPEAP SVPQRPAVPV VPEALSVPQP PVAPVAPEVP SVPQPPVAPV VPEAPSVPQP 120
  121 PVAPVAPEVP SVPQRPAVPV VPEAPSV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [635-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQPPAAPVVP EVPSVPQRPA VPVVPEAPSV PQPPAAPVVP EVPSVPQPPA VPVVPEAGQL  60
   61 NEPVVPPLPP HDETQEPQVG GDVKATEHTQ PTKTPAIVIY DYS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [738-857]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEEENEIELV ENEQIQILEF VDDGWWLGEN SKGQQGLFPS NYVEITGPNE TANNPPAEPQ  60
   61 AGGPGKSVKA IYDYQAQEDN ELSFFEDEII ANVDCVDPNW WEGECHGHRG LFPSNYVEEI 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.09691
Match: 1uecA
Description: p47pox (neutrophil cytosolic factor 1)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle