YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: ace2
Organism: Schizosaccharomyces pombe
Length: 533 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ace2.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
468.0 [0..3] [531..2344]
gi|109125970 - gi|109125970|ref|XP_001115785.1| PREDICTED: similar to zinc finger protein 665 [Macaca mulatta]
431.0 [0..1] [524..243]
gi|76678552 - gi|76678552|ref|XP_583095.2| PREDICTED: similar to Zinc finger protein 268 (Zinc finger protein HZF3...
425.0 [0..4] [532..649]
ZNF347 - zinc finger protein 347
gi|208968133 - gi|208968133|dbj|BAG73905.1| zinc finger protein 347 [synthetic construct]
412.0 [0..5] [532..270]

Back

Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSYLSSSS QKSFESFRQE ESPACNHSYQ RDYETFGDSK HTSFSSFAPF ENEVSLNQAV  60
   61 IPSPPSHLQN FQDQFDYSSV LKTPFNPLLE ANSAYFLSNQ ISLPDSHSYA SSFDASLSPP 120
  121 SSPLTCVSQI HTEQNFNNND AFSLTNSQQA FSEIGYDASN 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [161-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WIDELDSQQQ VLSFPEFDIP EIKTETCSNK DHLENFDYLS SSIPETSGPA SSVLPSSSQL  60
   61 ESFNEFMFLP SSPPGLDEIN GAPSFEELNF QISQPSPAHP VDLSSPETAP NISPVSPFAQ 120
  121 LVKLEPTSPQ KPSFALDSSF SHLDVCRHTD NQKAFAKLSS PAEYVSEFEK FSSVCDHGLD 180
  181 ISNANINNTL TQQFALSAPY ESCIVTKKPE P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.39794
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #3
Region A:
Residues: [372-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CITVKEEEQL APKIESADLS ITPQVTEHDS KPPVRISYDH RCKTRKQSTR ICRIPPETMA  60
   61 SLYCGPEADG KYVCLYNGCN KRIARKYNVE SHIQTHLSDR PYRCDLCKAG FVRHHDLKRH 120
  121 LRIHENGRPY VCECLKRFNR LDALNRHKQR NICVGGVDRR QH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 2gliA
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.31369346002275 bayes_pls_golite062009
transcription activator activity 2.19952417915035 bayes_pls_golite062009
transcription repressor activity 1.64349785387632 bayes_pls_golite062009
chromatin binding 1.53640935908107 bayes_pls_golite062009
sequence-specific DNA binding 1.42975942698743 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.0497955246512 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
transcription corepressor activity 0.10558148421807 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle