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View Structure Prediction Details

Protein: FBpp0309477, Ubqn-PA
Organism: Drosophila melanogaster
Length: 547 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0309477, Ubqn-PA.

Description E-value Query
Range
Subject
Range
gi|149039802, gi... - gi|48675852|ref|NP_446199.2| ubiquilin 1 [Rattus norvegicus], gi|47939201|gb|AAH72477.1| Ubiquilin 1...
266.0 [0..2] [542..21]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEGGSKRIN VVVKTPKDKK TVEVDEDSGI KDFKILVAQK FEAEPEQLVL IFAGKIMKDT  60
   61 DTLQMHNIKD NLTVHLVIKA PTRNNEQPAR QPADVRQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1wx7A
Description: Solution Structure of the N-terminal Ubiquitin-like Domain in the Human Ubiquilin 3 (UBQLN3)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small conjugating protein ligase activity 3.1015291294575 bayes_pls_golite062009
ubiquitin-protein ligase activity 2.66488876049395 bayes_pls_golite062009
binding 2.35732272412639 bayes_pls_golite062009
acid-amino acid ligase activity 2.21945212115988 bayes_pls_golite062009
protein tag 2.15059229834935 bayes_pls_golite062009
protein binding 1.86841453215444 bayes_pls_golite062009
transcription regulator activity 0.82919698244809 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.753885975469065 bayes_pls_golite062009
nucleic acid binding 0.744068636783535 bayes_pls_golite062009
DNA binding 0.635408380268467 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.536856055841234 bayes_pls_golite062009
kinase activity 0.506057697290914 bayes_pls_golite062009
SUMO ligase activity 0.412533160717297 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.410719674374641 bayes_pls_golite062009
transferase activity 0.236208643697075 bayes_pls_golite062009
protein kinase activity 0.038557482883633 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [98-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPFGLNQFGG LAGMEALGAG SNTFMDLQAR MQNELLNNGD MLRSLMDNPM VQQMMNNPDT  60
   61 MRQLITSNPQ MHDLMQRNPE ISHMLNNPDL LRQTMELARN PSMLQELMRS HDRAMSNLES 120
  121 VPGGYSALQR IYRDIQEPMM NAATESFGRN PFAGLVDGGG SGAGNNPQQG TENRNPLPNP 180
  181 WGGANSGTNG 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.973
Match: 1q1qA
Description: Crystal structure of human pregnenolone sulfotransferase (SULT2B1a) in the presence of PAP
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [288-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVGGSGAGNP TGDLPPNNVL NTPAMRSLLQ QMADNPAMMQ NLLNAPYTRS MMESMSQDPD  60
   61 MAARLLSSSP LMSNNPALQE QVRQMMPQFM AQMQNPEVMN MLTNPDAMNA ILQIQQGMEQ 120
  121 LRSAAPGLVG TLGIPPPPPG AGTGTNPASG DGSGGNSGAS TNNVSPSSGL NAGTGTPNLA 180
  181 PGGGP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [473-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAQLFNDFMM RMLNGMSNNA DNTQPPEVRY QSQLEQLNAM GFVNRDANLQ ALIATFGDIN  60
   61 AAVERLLSLN QLSLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.522879
Match: 1vejA
Description: Solution Structure of RSGI RUH-016, a UBA Domain from mouse cDNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.97462588597633 bayes_pls_golite062009
small conjugating protein binding 1.17371403847093 bayes_pls_golite062009
protein binding 1.07513578953037 bayes_pls_golite062009
transcription regulator activity 0.975058929011586 bayes_pls_golite062009
nucleic acid binding 0.964788761596736 bayes_pls_golite062009
ubiquitin binding 0.83381750627184 bayes_pls_golite062009
DNA binding 0.778785306874919 bayes_pls_golite062009
catalytic activity 0.25774924710417 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.172026786640155 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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