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View Structure Prediction Details

Protein: Hs3st-B-PA, FBpp...
Organism: Drosophila melanogaster
Length: 384 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hs3st-B-PA, FBpp....

Description E-value Query
Range
Subject
Range
gi|109113368 - gi|109113368|ref|XP_001114463.1| PREDICTED: similar to heparan sulfate D-glucosaminyl 3-O-sulfotrans...
272.0 [0..1] [383..1]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDTAATSAQ PAMIVMSIWC SSLSLSSRSL AIALVICVTL VYFSYSFNAC LLASISRSLQ  60
   61 QSNLRNLLAL TSSPRNETNN AANSSSSNSS SSRNSSSTTG APPAQTVTSS LD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [113-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAPKYQLLRQ QGLRPSRHLP DTLIIGVKKS GTRALLEFIR LHPDVRAAGS EVHFFDRHYQ  60
   61 RGLRWYRHHM PYTIEGQITM EKTPSYFVTK EVPQRVYHMN PATKLLIVVR DPVTRAISDY 120
  121 TQAASKKADM KLFEQLAFVN GSYSVVDTNW GPVKIGVYAR YLERWLLYFP LSQLLFISGE 180
  181 RLIMDPAYEI GRVQDFLGLK RVVTEKHFYF NATKGFPCLF KSEARSTPHC LGKTKGRNHP 240
  241 HIDPGAIERL REFYRPFNNK FYQLTGINFA WP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.39794
Match: 1t8uA
Description: Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP and tetrasaccharide substrate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.21604035604783 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.88448565327812 bayes_pls_golite062009
pyrophosphatase activity 1.81213329141196 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.79256074410868 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.7898097319166 bayes_pls_golite062009
transmembrane receptor activity 1.26314334516725 bayes_pls_golite062009
receptor activity 1.20313362488821 bayes_pls_golite062009
molecular transducer activity 1.13474466330485 bayes_pls_golite062009
signal transducer activity 1.13474466330485 bayes_pls_golite062009
G-protein coupled receptor activity 0.682467561649336 bayes_pls_golite062009
motor activity 0.50661339105747 bayes_pls_golite062009
purine nucleotide binding 0.442941451960958 bayes_pls_golite062009
purine ribonucleotide binding 0.440672169804309 bayes_pls_golite062009
ribonucleotide binding 0.440612929099368 bayes_pls_golite062009
nucleotide binding 0.433111366205869 bayes_pls_golite062009
[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity 0.22259207218243 bayes_pls_golite062009
nucleic acid binding 0.194779852865789 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle