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View Structure Prediction Details

Protein: U2af50-PA, FBpp0...
Organism: Drosophila melanogaster
Length: 416 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for U2af50-PA, FBpp0....

Description E-value Query
Range		 Subject
Range
gi|73976783 - gi|73976783|ref|XP_857420.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
 283.0 [0..27] [416..39]

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Predicted Domain #1
Region A:
Residues: [1-82] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYDDRERDR ERRRHRSRSR DRHRERSRDR RHHRNSRRKP SLYWDVPPPG FEHITPMQYK  60
   61 AMQASGQIPA SVVPDTPQTA VP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1agqA
Description: Glial cell-derived neurotrophic factor, GDNF
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [83-202] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVGSTITRQA RRLYVGNIPF GVTEEEMMEF FNQQMHLVGL AQAAGSPVLA CQINLDKNFA  60
   61 FLEFRSIDET TQAMAFDGIN LKGQSLKIRR PHDYQPMPGI TDTPAIKPAV VSSGVISTVV 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.522879
Match: 2g4bA
Description: No description for 2g4bA was found.

Predicted Domain #3
Region A:
Residues: [203-304] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDSPHKIFIG GLPNYLNDDQ VKELLLSFGK LRAFNLVKDA ATGLSKGYAF CEYVDLSITD  60
   61 QSIAGLNGMQ LGDKKLIVQR ASVGAKNAQN AANTTQSVML QV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.30103
Match: 2u2fA
Description: Splicing factor U2AF 65 KDa subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
U1 snRNA binding 3.02511982045347 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.425042944899091 bayes_pls_golite062009
transporter activity 0.417047632648771 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009
cytoskeletal protein binding 0.288834004308736 bayes_pls_golite062009
transmembrane transporter activity 0.288804044686487 bayes_pls_golite062009
snoRNA binding 0.0568636182001701 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00171911393626201 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [305-416] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGLSNVVTSG PPTEVLCLLN MVTPDELRDE EEYEDILEDI KEECTKYGVV RSVEIPRPIE  60
   61 GVEVPGCGKV FVEFNSVLDC QKAQQALTGR KFSDRVVVTS YFDPDKYHRR EF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1o0pA
Description: Splicing factor U2AF 65 KDa subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
U1 snRNA binding 3.02511982045347 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.425042944899091 bayes_pls_golite062009
transporter activity 0.417047632648771 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009
cytoskeletal protein binding 0.288834004308736 bayes_pls_golite062009
transmembrane transporter activity 0.288804044686487 bayes_pls_golite062009
snoRNA binding 0.0568636182001701 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00171911393626201 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle