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View Structure Prediction Details

Protein: FBpp0310125, FBp...
Organism: Drosophila melanogaster
Length: 597 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0310125, FBp....

Description E-value Query
Range
Subject
Range
gi|77996178, gi|... - gi|78044063|ref|YP_360551.1| long-chain-fatty-acid--CoA ligase [Carboxydothermus hydrogenoformans Z-...
544.0 [0..54] [595..7]

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Predicted Domain #1
Region A:
Residues: [1-597]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPAAQLLRM RSATAFGSAA TRSITTNRRQ RTTSTASAQR ERTQSVSETD KFLHYSPEDG  60
   61 YYKTSPFDPV TIPNVPLHEY VWRDFKKWER RTAAVCVITD RQYTFAQMRD ASAAFAVRLQ 120
  121 TKFNLQKPDV LAICLPNLPE YPIATLGAIE AGLTVTTVNP VYTPDEIARQ LTFSGAKFLV 180
  181 GTVSGFATLS QASKLVGRQI PIAVVRTSAE EALPEGAIDF SELTSTQNVR YEDLKAPKEA 240
  241 SADDMVFLPF SSGTTGLPKG VMLSHNNITS NCEQVQASLP LDLMGPQNTL PGVLPFFHIY 300
  301 GLTVVMLSKL GQGCRLATMP CFKPDDFMRS LDKYQGSILN LVPPIALFMI NHPKLTQETA 360
  361 PHLKVVMSGA APIGQHDVER FLNKFPNTVF KQGYGMTEAS PVVLLTPEGN KVYASTGVLP 420
  421 ASTEAKIVPL DGSDAKGVGP RTTGELCVRG PQVMAGYLNN DEANQVTFYP GNWLRSGDVA 480
  481 FYDEDGLFYI TDRMKELIKV KGFQVPPAEL EAVLRDHPKI LEAAVFGIPH EFNGEAPRAI 540
  541 VVLRQGEKAS AEEISAYVAE RVAHYKKLEG GVIFVDEVPK NPTGKILRRE LKEKFSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 114.0
Match: 1ba3A
Description: FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming carbon-sulfur bonds 5.10123876514454 bayes_pls_golite062009
fatty acid ligase activity 4.83067429373059 bayes_pls_golite062009
long-chain fatty acid-CoA ligase activity 4.72692389032116 bayes_pls_golite062009
acid-thiol ligase activity 4.28278725989432 bayes_pls_golite062009
CoA-ligase activity 4.12850865352867 bayes_pls_golite062009
acetate-CoA ligase activity 3.83959707137518 bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) 2.74744781333102 bayes_pls_golite062009
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity 2.74744781333102 bayes_pls_golite062009
luciferin monooxygenase activity 2.67396462766343 bayes_pls_golite062009
ligase activity 2.49556073715112 bayes_pls_golite062009
catalytic activity 1.83545185797733 bayes_pls_golite062009
binding 0.903437109563498 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.464663038956639 bayes_pls_golite062009
transcription regulator activity 0.245590924269919 bayes_pls_golite062009

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