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View Structure Prediction Details

Protein: rdgB-PA, rdgB-PD...
Organism: Drosophila melanogaster
Length: 1259 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rdgB-PA, rdgB-PD....

Description E-value Query
Range
Subject
Range
rdgB-PB, rdgB-PF - The gene retinal degeneration B is referred to in FlyBase by the symbol Dmel\rdgB (CG11111, FBgn0003...
1539.0 [0..1] [1247..1]

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Predicted Domain #1
Region A:
Residues: [1-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIKEYRIPL PLTVEEYRIA QLYMIAKKSR EESHGEGSGV EIIINEPYKD GPGGNGQYTK  60
   61 KIYHVGNHLP GWIKSLLPKS ALTVEEEAWN AYPYTRTRYT CPFVEKFSLD IETYYYPDNG 120
  121 YQDNVFQLSG SDLRNRIVDV IDIVKDQLWG GDYVKEEDPK HFVSDKTGRG PLAEDWLEEY 180
  181 WREVKGKKQP TPRNMSLMTA YKICRVEFRY WGMQTKLEKF IHDVALRKMM LRAHRQAWAW 240
  241 QDEWFGLTIE DIRELERQTQ LALAKKMGGG EECSD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 121.0
Match: 1kcmA
Description: Phoshatidylinositol transfer protein, PITP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipid transporter activity 5.13837461289632 bayes_pls_golite062009
lipid transporter activity 4.4358073696145 bayes_pls_golite062009
phosphatidylinositol transporter activity 2.88424241201993 bayes_pls_golite062009
transporter activity 2.27726025087174 bayes_pls_golite062009
substrate-specific transporter activity 2.15798050058248 bayes_pls_golite062009
binding 2.03322388415011 bayes_pls_golite062009
sterol binding 1.69869946950041 bayes_pls_golite062009
cholesterol binding 1.2916246557678 bayes_pls_golite062009
transmembrane transporter activity 1.09413284791115 bayes_pls_golite062009
phosphatidylcholine transmembrane transporter activity 1.08589653256802 bayes_pls_golite062009
cholesterol transporter activity 0.971604403704219 bayes_pls_golite062009
sterol transporter activity 0.84702583633369 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.584604660695011 bayes_pls_golite062009
protein binding 0.43929659331502 bayes_pls_golite062009
ion transmembrane transporter activity 0.295257921753146 bayes_pls_golite062009
active transmembrane transporter activity 0.286459038638072 bayes_pls_golite062009
primary active transmembrane transporter activity 0.265156292873733 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.256503527440737 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.21859262454477 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.215063584310921 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.214776368903272 bayes_pls_golite062009
lipid binding 0.207466011012419 bayes_pls_golite062009
cation transmembrane transporter activity 0.0954103313829049 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0415343979510595 bayes_pls_golite062009
catalytic activity 0.0116392906163881 bayes_pls_golite062009
pyrophosphatase activity 0.00274551209125462 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [276-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSVSEPYVST AATAASTTGS ERKKSAPAVP PIVTQQPPSA EASSDEEGEE EEDDDEDEND  60
   61 AIGTGVDLSA N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [347-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGGSAQRSRS QSIQMAQKGK FGSKGALHSP VGSAHSFDLQ VANWRMERLE VDSKSNSDEE  60
   61 FFDCLDTNET NSLAKWSSLE LLGEGDDSPP PHGGPSSAAS VGGRGNSRQE DSIFNQDFLM 120
  121 RVASERGNKR QLRSSASVDR SHDSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [492-571]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPGSPSTPSC PTTILILVVH AGSVLDAASE LTAKKSDVTT FRGSFEAVMR QHYPSLLTHV  60
   61 TIKMVPCPSI CTDALGILSS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [572-741]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSPYSFDASP SAADIPNIAD VPIGAIPLLS VASPEFHETV NKTVAAANIV YHEFLKSEEG  60
   61 HGFSGQIVML GDSMGSLLAY EALCRSNGSQ PGTASGASNS GGDAATNINT HNPLSPRNSR 120
  121 LDDDERFIEA DLDAKRLLVA PSPRRRRSSS SSDSRATKLD FEVCDFFMFG 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [742-928]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPLSVVLAAR KLHDAKAALP RPNCHQVYNL FHPTDPIASR LEPLLSARFS ILAPVNVPRY  60
   61 AKYPLGNGQP LHLLEVIQSH PQHFNDGNNL LAGRRLSDAS MQSTISGLIE NVSLSTIHAL 120
  121 QNKWWGTKRL DYALYCPEGL SNFPAHALPH LFHASYWESP DVIAFILRQI GKFEGIPFVG 180
  181 SNDDKDN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 92.49485
Match: PF02862.8
Description: No description for PF02862.8 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [929-1259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASFHPGQPRE KWIKKRTSVK LKNVAANHRA NDVIVQEGRE QRLNARFMYG PLDMITLHGE  60
   61 KVDVHIMKDP PAGEWTFLST EVTDKNGRIS YSIPDQVSLG YGIYPVKMVV RGDHTSVDCY 120
  121 MAVVPPLTEC VVFSIDGSFT ASMSVTGRDP KVRAGAVDVC RHWQELGYLL IYITGRPDMQ 180
  181 QQRVVSWLSQ HNFPHGLISF ADGLSTDPLG HKTAYLNNLV QNHGISITAA YGSSKDISVY 240
  241 TNVGMRTDQI FIVGKVGKKL QSNATVLSDG YAAHLAGLQA VGGSRPAKGN ARMVIPRGCF 300
  301 NLPGQTANPR RRRYLERKTV SSCCLMVFQT T

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.53
Match: 2i33A
Description: No description for 2i33A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle