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View Structure Prediction Details

Protein: FBpp0303704, FBp...
Organism: Drosophila melanogaster
Length: 354 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0303704, FBp....

Description E-value Query
Range
Subject
Range
gi|73976787 - gi|73976787|ref|XP_857499.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 2 ...
268.0 [0..12] [353..77]

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Predicted Domain #1
Region A:
Residues: [1-118]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYGNNNPGSN NNNGGYPPYG YNNKSSGGRG FGMSHSLPSG MSRYAFSPQD TEFSFPSSSS  60
   61 RRGYNDFPGC GGSGGNGGSA NNLGGGNMCH LPPMASNNSL NNLCGLSLGS GGSDDLMN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [119-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPRASNTNLI VNYLPQDMTD RELYALFRAI GPINTCRIMR DYKTGYSFGY AFVDFTSEMD  60
   61 SQRAIKVLNG ITVRNKRLKV SYARPGGESI KDTNLYVTNL PRTITDDQLD TIFGKYGSIV 120
  121 QKNILRDKLT GRPRGVAFVR YNKREEAQEA ISALNNVIPE GGSQPLSVRL AEEHGKAKAA 180
  181 HFMSQMGVVP ANVPPPPPQP PAHMAAAFNM MHRGRSIKSQ QRFQNSHPYF DAKKFI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.69897
Match: 3sxlA
Description: Sex-lethal protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
U1 snRNA binding 3.02511982045347 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
structural molecule activity 2.78501986457503 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
U2 snRNA binding 1.34078165372485 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription repressor activity 1.06887262556449 bayes_pls_golite062009
structure-specific DNA binding 0.970421843909091 bayes_pls_golite062009
single-stranded DNA binding 0.87522799562879 bayes_pls_golite062009
transcription factor activity 0.873765500321315 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
mRNA 5'-UTR binding 0.625848256054783 bayes_pls_golite062009
translation regulator activity 0.583455818533482 bayes_pls_golite062009
translation repressor activity, nucleic acid binding 0.461000905454505 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.333822192939807 bayes_pls_golite062009

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