YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: dx-PA
Organism: Drosophila melanogaster
Length: 738 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dx-PA.

Description E-value Query
Range
Subject
Range
gi|28316915 - gi|28316915|gb|AAO39479.1| RE59350p [Drosophila melanogaster]
493.0 [0..28] [738..1]

Back

Predicted Domain #1
Region A:
Residues: [1-262]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSAGSAAS GSVVPGGGGS AASSCATMAL STAGSGGPPV NHAHAVCVWE FESRGKWLPY  60
   61 SPAVSQHLER AHAKKLTRVM LSDADPSLEQ YYVNVRTMTQ ESEAETAGSG LLTIGVRRMF 120
  121 YAPSSPAGKG TKWEWSGGSA DSNNDWRPYN MHVQCIIEDA WARGEQTLDL CNTHIGLPYT 180
  181 INFCNLTQLR QPSGPMRSIR RTQQAPYPLV KLTPQQANQL KSNSASVSSQ YNTLPKLGDT 240
  241 KSLHRVPMTR QQHPLPTSHQ VQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.39794
Match: 2a90A
Description: Crystal Structure of the tandem WWE domain of Drosophila Deltex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
Notch binding 2.92660801070981 bayes_pls_golite062009
protein binding 1.92218838849639 bayes_pls_golite062009
binding 1.6234987165625 bayes_pls_golite062009
receptor binding 0.681627758990235 bayes_pls_golite062009
protein domain specific binding 0.169218013172214 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [263-397]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQHQHQHQQ QQQQQHHHQH QQQQHQQQQQ HQMQHHQIHH QTAPRKPPKK HSEISTTNLR  60
   61 QILNNLNIFS SSTKHQSNMS TAASASSSSS SASLHHANHL SHAHFSHAKN MLTASMNSHH 120
  121 SRCSEGSLQS QRSSR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [398-524]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSHRSRSRT RTSDTDTNSV KSHRRRPSVD TVSTYLSHES KESLRSRNFA ISVNDLLDCS  60
   61 LGSDEVFVPS LPPSSLGERA PVPPPLPLHP RQQQQQQQQQ QQLQMQQQQQ AQQQQQQSIA 120
  121 GSIVGVD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [525-637]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PASDMISRFV KVVEPPLWPN AQPCPMCMEE LVHSAQNPAI SLSRCQHLMH LQCLNGMIIA  60
   61 QQNEMNKNLF IECPVCGIVY GEKVGNQPIG SMSWSIISKN LPGHEGQNTI QIV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 1v87A
Description: Solution Structure of the Ring-H2 Finger Domain of Mouse Deltex Protein 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.64803540957326 bayes_pls_golite062009
binding 2.14721962003828 bayes_pls_golite062009
small conjugating protein ligase activity 0.587037280321105 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.457219654632707 bayes_pls_golite062009
transcription factor binding 0.0370371235994398 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [638-738]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YDIASGLQTE EHPHPGRAFF AVGFPRICYL PDCPLGRKVL RFLKIAFDRR LLFSIGRSVT  60
   61 TGREDVVIWN SVDHKTQFNM FPDPTYLQRT MQQLVHLGVT D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle