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View Structure Prediction Details

Protein: dnc-PB, FBpp0305507
Organism: Drosophila melanogaster
Length: 1209 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dnc-PB, FBpp0305507.

Description E-value Query
Range
Subject
Range
gi|21430658 - gi|21430658|gb|AAM51007.1| RE53611p [Drosophila melanogaster]
920.0 [0..1] [1209..1]

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Predicted Domain #1
Region A:
Residues: [1-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRLARFTQG FSFNKNVAKH RGSGSSNGTG NGSGTGNGQG LGGSCSANGL AATGGVGGGG  60
   61 GSGSGGGGCG SGSGSGSGKR KSKARTKCFG GTVFRCCLPC RGGGSAAPAT SPPQTPAQTP 120
  121 DELKVIPEDC NLEKSAEQKR DLLERNNKED DLLNRTVSGS ELDLYGG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1giyB
Description: 70S ribosome functional complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [168-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGGGTKKHSL ADTIDTSVTT PISLKTLIND VDEELDQQLS AADIAAASLA SGLVARRAEP  60
   61 ETLSDASVSP TAVVQQQQQQ QQQLQQPLLQ SQPHFVPSSG NILSQVTLYS GSNPSTNPCQ 120
  121 SAVQNQGQNS NPN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [301-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNQNPNTNPN QNQQRCSCQP QTSPLPHIKE EEESDQANFK HQTSLKEHQP LPPPITIATG  60
   61 YCGSCESVHH SSATSSSAGT VPPGGQQTQE YIAGTSSTPS PRIKLKFRKP HKSCWSRIVL 120
  121 APIGSAGGSS SATTVIGSNS NETLASSSTT GGTATTTQNS SSVSVAAHHR LTSSSASALA 180
  181 TSHPSNSQLL PTSKMQAEQG SIGDLQKYHS RYLKNRRHTL A

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [522-759]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVRFDVENGQ GARSPLEGGS PSAGLVLQNL PQRRESFLYR SDSDFEMSPK SMSRNSSIAS  60
   61 ERFKEQEASI LVDRSHGEDL IVTPFAQILA SLRSVRNNLL SLTNVPASNK SRRPNQSSSA 120
  121 SRSGNPPGAP LSQGEEAYTR LATDTIEELD WCLDQLETIQ THRSVSDMAS LKFKRMLNKE 180
  181 LSHFSESSRS GNQISEYICS TFLDKQQEFD LPSLRVEDNP ELVAANAAAG QQSAGQYA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [760-1209]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSRSPRGPPM SQISGVKRPL SHTNSFTGER LPTFGVETPR ENELGTLLGE LDTWGIQIFS  60
   61 IGEFSVNRPL TCVAYTIFQS RELLTSLMIP PKTFLNFMST LEDHYVKDNP FHNSLHAADV 120
  121 TQSTNVLLNT PALEGVFTPL EVGGALFAAC IHDVDHPGLT NQFLVNSSSE LALMYNDESV 180
  181 LENHHLAVAF KLLQNQGCDI FCNMQKKQRQ TLRKMVIDIV LSTDMSKHMS LLADLKTMVE 240
  241 TKKVAGSGVL LLDNYTDRIQ VLENLVHCAD LSNPTKPLPL YKRWVALLME EFFLQGDKER 300
  301 ESGMDISPMC DRHNATIEKS QVGFIDYIVH PLWETWADLV HPDAQDILDT LEENRDYYQS 360
  361 MIPPSPPPSG VDENPQEDRI RFQVTLEESD QENLAELEEG DESGGESTTT GTTGTTAASA 420
  421 LSGAGGGGGG GGGMAPRTGG CQNQPQHGGM 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 141.0
Match: 2fm0A
Description: No description for 2fm0A was found.

Predicted functions:

Term Confidence Notes
cyclic-nucleotide phosphodiesterase activity 4.70762025272187 bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity 4.66767157264894 bayes_pls_golite062009
phosphoric diester hydrolase activity 4.40961779134517 bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity 3.68838886134169 bayes_pls_golite062009
3',5'-cyclic-GMP phosphodiesterase activity 2.64567538445993 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.26293733853576 bayes_pls_golite062009
hydrolase activity 1.17086565360856 bayes_pls_golite062009
catalytic activity 1.07048165010262 bayes_pls_golite062009
binding 0.994379083280533 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.893957699588543 bayes_pls_golite062009
protein binding 0.162314119157812 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle