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View Structure Prediction Details

Protein: sc-PA
Organism: Drosophila melanogaster
Length: 345 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sc-PA.

Description E-value Query
Range
Subject
Range
gi|3618335 - gi|3618335|dbj|BAA33212.1| scute [Drosophila simulans]
226.0 [0..1] [345..1]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNNNNTTKS TTMSSSVLST NETFPTTINS ATKIFRYQHI MPAPSPLIPG GNQNQPAGTM  60
   61 PIKTRKYTPR GMALTRCSES VSSLSPGSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [90-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAPYNVDQSQ SVQRRNARER NRVKQVNNSF ARLRQHIPQS IITDLTKGGG RGPHKKISKV  60
   61 DTLRIAVEYI RRLQDLVDDL NGGSNIGANN AVTQLQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.30103
Match: 1am9A
Description: SREBP-1a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.39500382187264 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.42306484786159 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
protein binding 1.59929864805879 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
promoter binding 0.8576109846276 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [187-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CLDESSSHSS SSSTCSSSGH NTYYQNTISV SPLQQQQQLQ RQQFNHQPLT ALSLNTNLVG  60
   61 TSVPGGDAGC VSTSKNQQTC HSPTSSFNSS MSFDSGTYEG VPQQISTHLD RLDHLDNELH 120
  121 THSQLQLKFE PYEHFQLDEE DCTPDDEEIL DYISLWQEQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle