| Protein: | Sirt7-PA |
| Organism: | Drosophila melanogaster |
| Length: | 771 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sirt7-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
439.0 | [0..21] | [771..1] |
|
Region A: Residues: [1-426] |
1 11 21 31 41 51
| | | | | |
1 MEKDLGEEKD QDQEQNTEME PKQEMDVAQS YITRAKMNPA KKDNEKRRRK DAMRRVSMIL 60
61 RKCDSMRTTE DRQFLEKHPD MVKTTKKRKE RVEIYKERVV EREDAPHVIE AKVEQLANII 120
121 SQAKHLVCYT GAGISTAALI PDYRGSQGIW TLLQKGQDIG EHDLSSANPT YTHMALYELH 180
181 RRRLLHHVVS QNCDGLHLRS GLPRNSLSEI HGNMYVEVCK NCRPNSVYWR QFDTTEMTAR 240
241 YCHKTHRLCH RCSEPLYDTI VHFGERGNVK WPLNWAGATA NAQRADVILC LGSSLKVLKK 300
301 YTWLWQMDRP ARQRAKICVV NLQWTPKDAI ASIKINGKCD QVMAQLMHLL HIPVPVYTKE 360
361 KDPIFAHASL LMPEELHTLT QPLLKNADEE EAFTTTTEET QDSTISSESC SFNYSDLPIG 420
421 KGPRIR
|
| Detection Method: |  |
| Confidence: | 58.0 |
| Match: | 1j8fA |
| Description: | Sirt2 histone deacetylase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.68732752141642 | bayes_pls_golite062009 |
| transcription regulator activity | 1.39353160159826 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity | 0.875291904235447 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 0.875291904235447 | bayes_pls_golite062009 |
| catalytic activity | 0.739210399081789 | bayes_pls_golite062009 |
| DNA binding | 0.728790202227599 | bayes_pls_golite062009 |
| histone deacetylase activity | 0.678257037571674 | bayes_pls_golite062009 |
| protein deacetylase activity | 0.667574326888104 | bayes_pls_golite062009 |
| nucleic acid binding | 0.620294268351623 | bayes_pls_golite062009 |
| protein binding | 0.0198646008296066 | bayes_pls_golite062009 |
|
Region A: Residues: [427-564] |
1 11 21 31 41 51
| | | | | |
1 TPIKNGRRVK TNLELRQKFK TLNGQDEEIK VEHVKTNGEV KTEKDLITLE SSIKIETEVK 60
61 LEKLECSDTN FQQELKLLEL LPKLEPLSLK EETEETPSNG FPELPKLVAI QKTHAECLSA 120
121 VPTESRLKPL QLPPLVPI
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [565-690] |
1 11 21 31 41 51
| | | | | |
1 GAPLSTPFVE PKLVLPPASQ SSSIQIKSEG DGDSSTENDN EEEEESELAQ MDLLRQNNDE 60
61 ELLRQLPTWY DAKYAYSGLH SILIPPPADL NIWNSQVVPN FAMNRSAASC FFCFDRYAEL 120
121 ECQFYR
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [691-771] |
1 11 21 31 41 51
| | | | | |
1 RWNLSQRKHK KRARSGRFVV CECCPTSDDD DDYDENISLA HIAAAETAKR RQQLSTSFPR 60
61 KLARTQAGWY GKGYKKGRKR R
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
