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View Structure Prediction Details

Protein: FBpp0311419, fkh...
Organism: Drosophila melanogaster
Length: 510 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0311419, fkh....

Description E-value Query
Range
Subject
Range
gi|78214236 - gi|78214236|gb|ABB36440.1| RE06859p [Drosophila melanogaster]
179.0 [0..1] [510..1]

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Predicted Domain #1
Region A:
Residues: [1-100]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKLYAEPPP SSAPVSMASS GGGGPPSGGG GGGGGGGGGG PPPPSNNNPN PTSNGGSMSP  60
   61 LARSAYTMNS MGLPVGGMSS VSPQAAATFS SSVLDSAAAV 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.97
Match: 1pk8A
Description: Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [101-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASMSASMSAS MSASMNASMN GSMGAAAMNS MGGNCMTPSS MSYASMGSPL GNMGGCMAMS  60
   61 AASMSAAGLS GTYGAMPPGS REMETGSPNS LGRSRVDKPT TYR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 22.49485
Match: PF08430.3
Description: No description for PF08430.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [204-342]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSYTHAKPPY SYISLITMAI QNNPTRMLTL SEIYQFIMDL FPFYRQNQQR WQNSIRHSLS  60
   61 FNDCFVKIPR TPDKPGKGSF WTLHPDSGNM FENGCYLRRQ KRFKDEKKEA IRQLHKSPSH 120
  121 SSLEATSPGK KDHEDSHHM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.39794
Match: 1d5vA
Description: Adipocyte-transcription factor FREAC-11 (s12, fkh-14)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 5.08959163553491 bayes_pls_golite062009
nucleic acid binding 4.99681957904233 bayes_pls_golite062009
transcription factor activity 4.33152142980289 bayes_pls_golite062009
transcription repressor activity 3.85678231380989 bayes_pls_golite062009
transcription activator activity 3.70589483230587 bayes_pls_golite062009
sequence-specific DNA binding 3.58179858678904 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
protein binding 1.80415286835431 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.2723726467408 bayes_pls_golite062009
specific transcriptional repressor activity 0.96257232341735 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
transcription corepressor activity 0.322180400748724 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.23177057841536 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [343-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HHHHHSRLDH HQHHKEAGGA SIAGVNVLSA AHSKDAEALA MLHANAELCL SQQPQHVPTH  60
   61 HHHQHHQLQQ EELSAMMANR CHPSLITDYH SSMHPLKQEP SGYTPSSHPF SINRLLPTES 120
  121 KADIKMYDMS QYAGYNALSP LTNSHAALGQ DSYYQSLGYH APAGTTSL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle