| Protein: | Mes-4-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1427 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Mes-4-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
342.0 | [0..1] | [1425..1] |
|
Region A: Residues: [1-216] |
1 11 21 31 41 51
| | | | | |
1 MKLSTDAHSE IEGDAAHGNV LCNSASDSLT ATDEVAAGND ESVATEGDDV EIPRDTNNST 60
61 PVRLLDKPGQ NPVQNGAQPA AEESELESQR QTPVQKQQQQ RVSMVNRKRD LINLQSALSP 120
121 KYIGYANANS PTPLSDSDDT IRTTRRRVNQ AAALNNSSAG ETLAHDNASP RTPGGGGGGG 180
181 GDDSANQLLS KTYMSPIEKL LIKNGASSPN STGFEA
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [217-365] |
1 11 21 31 41 51
| | | | | |
1 GSEDLGIRPI VRKHVKRKMK RVPKAKVTLE LDEKNQQEVD EKSVKTEPID EEVDRTDEAP 60
61 TQEAQTTAIS IKSETEAEHK AAVDVHIKQE DTIRLDIVNN PVESTSIVIT EEPKDLEKST 120
121 EELAFALPLA SSTEVDLKSP PDLSSTALA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [366-515] |
1 11 21 31 41 51
| | | | | |
1 TSIKSPSSVS IDSAKGLSIV TDPGWPTYQV GDLFWGKVFS YCFWPCMVCP DPLGQIVGNM 60
61 PSHPQRSSLD NANVPIQVHV RFFADNGRRN WIKPENLLTF AGLKAFDDMR EELRIKHGPK 120
121 SAKYRQMVPK RTKVVIWRQA IEEAQAMTQI
|
| Detection Method: | |
| Confidence: | 7.0 |
| Match: | 2gfuA |
| Description: | No description for 2gfuA was found. |
|
Region A: Residues: [516-690] |
1 11 21 31 41 51
| | | | | |
1 PYSDRLEKFY QTYENVVTLN RQKRKRTKYM MQDTSDVGSS LYDSTDNLHN KQGTQLLAVK 60
61 RERSESPFSP AFSPVKSKNE KRAKRRKLSN GTEADTGSNS MAVTPSQTET TVDSSAYENP 120
121 EFRQLLSAVM EYVMMNRSDE KVEKVLLSVV SNIWSLKQIQ LRELERDLAS GEIEE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [691-812] |
1 11 21 31 41 51
| | | | | |
1 PLGSSVVGRG SGVGTIKRLS NRLMTMMVRR SMTPVVTPST TPAPSEPDRR LSEPPKTKKP 60
61 VNRPIEEVIE DILQLDSKYL FRGLSREPIC KYCYQAGSDL VRCSRTCSSW LHADCLERKV 120
121 TG
|
| Detection Method: | |
| Confidence: | 1.08 |
| Match: | 1r79A |
| Description: | Solution Structure of The C1 Domain of The Human Diacylglycerol Kinase Delta |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.28414942114785 | bayes_pls_golite062009 |
| transcription regulator activity | 2.3594533055858 | bayes_pls_golite062009 |
| nucleic acid binding | 1.81629978306019 | bayes_pls_golite062009 |
| DNA binding | 1.66283166928615 | bayes_pls_golite062009 |
| protein binding | 1.11019507232162 | bayes_pls_golite062009 |
| transcription factor activity | 1.06673352248936 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.675335570837432 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.671077806185763 | bayes_pls_golite062009 |
| catalytic activity | 0.216721136299042 | bayes_pls_golite062009 |
|
Region A: Residues: [813-1014] |
1 11 21 31 41 51
| | | | | |
1 APMPKIGSRK ALVIPPTSKS PSPDEDHVTA DAKEVVAVGT SLVCHECNVG EPEGCVICHQ 60
61 VESPAVPSTP RKEDSSSHTP IEDKLLTCSQ PMCGKRFHTS CCKYWPQASS SKHSARCPRH 120
121 VCHTCVSDDP SGKFQQLGSS KLAKCVRCPA TYHQLSKCIP AGTQMLNTTN IICPRHNIAK 180
181 ADAHVNVLWC YICVKGGELV CC
|
| Detection Method: | |
| Confidence: | 3.09691 |
| Match: | 1igrA |
| Description: | Type 1 insulin-like growth factor receptor extracellular domain; Type 1 insulin-like growth factor receptor Cys-rich domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.68068574919022 | bayes_pls_golite062009 |
| protein binding | 1.89567090642897 | bayes_pls_golite062009 |
| growth factor binding | 1.78764054532907 | bayes_pls_golite062009 |
| insulin-like growth factor II binding | 1.61780711385 | bayes_pls_golite062009 |
| insulin-like growth factor binding | 1.14132310810584 | bayes_pls_golite062009 |
| insulin-like growth factor I binding | 0.715089814495633 | bayes_pls_golite062009 |
| catalytic activity | 0.271811389148807 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activator activity | 0.225770989190604 | bayes_pls_golite062009 |
|
Region A: Residues: [1015-1122] |
1 11 21 31 41 51
| | | | | |
1 ETCPIAVHAH CRNIPIKTNE SYICEECESG RLPLYGEIVW AKFNNFRWWP AIILPPTEVP 60
61 SNILKKAHGE NDFVVRFFGT HDHGWISRRR VYLYIEGDTG DGHKTKSQ
|
| Detection Method: | |
| Confidence: | 6.221849 |
| Match: | 2daqA |
| Description: | No description for 2daqA was found. |
| Term | Confidence | Notes |
| binding | 3.61058244718631 | bayes_pls_golite062009 |
| transcription repressor activity | 3.06808416304746 | bayes_pls_golite062009 |
| transcription regulator activity | 2.87915752987189 | bayes_pls_golite062009 |
| nucleic acid binding | 1.99409428066103 | bayes_pls_golite062009 |
| DNA binding | 1.99122459938277 | bayes_pls_golite062009 |
| protein binding | 1.6693185254069 | bayes_pls_golite062009 |
| chromatin binding | 1.64603851743141 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.55732936245077 | bayes_pls_golite062009 |
| transcription factor binding | 1.41819104451617 | bayes_pls_golite062009 |
| transcription cofactor activity | 1.23808324966394 | bayes_pls_golite062009 |
| histone methyltransferase activity | 1.09290857177628 | bayes_pls_golite062009 |
| transcription factor activity | 1.09191102986161 | bayes_pls_golite062009 |
| methylated histone residue binding | 0.93051370247257 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 0.72077437792468 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 0.72077437792468 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 0.72077437792468 | bayes_pls_golite062009 |
| retinoid X receptor binding | 0.47657909093375 | bayes_pls_golite062009 |
| retinoic acid receptor binding | 0.43555270589681 | bayes_pls_golite062009 |
| unmethylated CpG binding | 0.300145179661899 | bayes_pls_golite062009 |
| transcription activator activity | 0.0981008314930329 | bayes_pls_golite062009 |
| fibroblast growth factor binding | 0.031681227093159 | bayes_pls_golite062009 |
|
Region A: Residues: [1123-1427] |
1 11 21 31 41 51
| | | | | |
1 LFRNYTTGVE EASRFLPIIK ARRQEQDMER QSGNKLHPPP YVKIKTNKAV PPLRFSQNLE 60
61 DLSTCNCLPV DEHPCGPEAG CLNRMLFNEC NPEYCKAGSL CENRMFEQRK SPRLEVVYMN 120
121 ERGFGLVNRE PIAVGDFVIE YVGEVINHAE FQRRMEQKQR DRDENYYFLG VEKDFIIDAG 180
181 PKGNLARFMN HSCEPNCETQ KWTVNCIHRV GIFAIKDIPV NSELTFNYLW DDLMNNSKKA 240
241 CFCGAKRCSG EIGGKLKDDA VKAHAKLKQM RRAKASAVRI HVKPKKTPKV KHISADDEPM 300
301 DAKDE
|
| Detection Method: | |
| Confidence: | 14.39794 |
| Match: | 2igqA |
| Description: | No description for 2igqA was found. |
