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View Structure Prediction Details

Protein: bigmax-PA
Organism: Drosophila melanogaster
Length: 254 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bigmax-PA.

Description E-value Query
Range
Subject
Range
gi|11761698 - gi|11761698|gb|AAG40148.1|AF213669_1 bHLHZip transcription factor BIGMAX [Drosophila melanogaster]
176.0 [0..1] [254..1]
gi|195144134, gi... - gi|195144134|ref|XP_002013051.1| GL23593 [Drosophila persimilis], gi|194101994|gb|EDW24037.1| GL2359...
gi|125774095|ref... - GA17397-PA [Drosophila pseudoobscura], GA17397 [Drosophila pseudoobscura pseudoobscura]
gi|125774095, gi... - gi|54638042|gb|EAL27444.1| GA17397 [Drosophila pseudoobscura pseudoobscura], gi|125774095|ref|XP_001...
150.0 [0..1] [254..1]
gi|4704419 - gi|4704419|gb|AAD28084.1| WS basic-helix-loop-helix leucine zipper protein [Homo sapiens]
146.0 [0..63] [250..20]
gi|118780997, gi... - gi|118780997|ref|XP_311211.3| ENSANGP00000019116 [Anopheles gambiae str. PEST], gi|116130212|gb|EAA0...
140.0 [0..27] [233..1]
gi|73994515 - gi|73994515|ref|XP_859822.1| PREDICTED: similar to MondoA isoform 3 [Canis familiaris]
136.0 [0..2] [251..643]
gi|114647538 - gi|114647538|ref|XP_509441.2| PREDICTED: MLX interacting protein [Pan troglodytes]
135.0 [0..26] [250..575]
MLXPL_RAT - Carbohydrate-responsive element-binding protein OS=Rattus norvegicus GN=Mlxipl PE=1 SV=1
134.0 [0..23] [250..609]
gi|50756401 - gi|50756401|ref|XP_415149.1| PREDICTED: similar to MondoA [Gallus gallus]
134.0 [0..5] [254..1281]

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Predicted Domain #1
Region A:
Residues: [1-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDNNNALAT KEDVFGMEHD QDHTSKHYSR CSSAGSTHTP NSSAHNSDDD DDSGDARHSA  60
   61 AANSTLSYKE RRREAHTQAE QKRRDAIKKG YDSLQELVPR CQPNDSSGYK LSKALILQKS 120
  121 IEYIGYLNQQ KLKQEDEGSA LQKEVTALRI IKNGYE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.154902
Match: 1nkpA
Description: Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
nucleic acid binding 4.75270293029792 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.48787404513864 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
protein binding 1.59929864805879 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 1.46304579811572 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [157-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMLQHQQANP GPEEARLTDE AKFQVFQAIM EEMFETFQHI PMENFKQLTT GIIPWLEEHC  60
   61 KPHILRNILS RTLQQMAQEA MEKQELQAME QESSEGFS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle