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View Structure Prediction Details

Protein: FBpp0305403, FBp...
Organism: Drosophila melanogaster
Length: 470 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0305403, FBp....

Description E-value Query
Range
Subject
Range
gi|73976777 - gi|73976777|ref|XP_857296.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
323.0 [0..8] [469..100]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDESQPKTLY VGNLDSSVSE DLLIALFSTM GPVKSCKIIR EPGNDPYAFI EYSNYQAATT  60
   61 ALTAMNKRLF LEKEIKVNWA TSPGNQPKTD ISSHHHIFVG DLSPEIETET LREAFAPFGE 120
  121 ISNCRIVRDP HTMKSKGYAF VSFVKKAEAE NAIQAMNGQW IGSRSIRTNW STRKLPPPRE 180
  181 PSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.0
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
U1 snRNA binding 4.22094068431436 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.56454315220334 bayes_pls_golite062009
U2 snRNA binding 1.34078165372485 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 0.873765500321315 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [184-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGGQGGGMGG GPGNGSGVKG SQRHTFEEVY NQSSPTNTTV YCGGFPPNVI SDDLMHKHFV  60
   61 QFGPIQDVRV FKDKGFSFIK FVTKEAAAHA IEHTHNSEVH GNLVKCFWGK ENGGDNSANN 120
  121 LNAAAAAAAA SANVAAVAAA NAAVAAG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.08
Match: 1sjrA
Description: NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6.40066880991253 bayes_pls_golite062009
RNA binding 6.32219487559982 bayes_pls_golite062009
mRNA binding 4.87640532914983 bayes_pls_golite062009
nucleic acid binding 4.65259034341669 bayes_pls_golite062009
U1 snRNA binding 3.93490468939017 bayes_pls_golite062009
snRNA binding 3.77997752511163 bayes_pls_golite062009
binding 3.48033873254013 bayes_pls_golite062009
poly-pyrimidine tract binding 2.7133834347239 bayes_pls_golite062009
single-stranded RNA binding 2.55628738360472 bayes_pls_golite062009
transcription regulator activity 2.2045206027152 bayes_pls_golite062009
DNA binding 1.80828042019548 bayes_pls_golite062009
structural molecule activity 1.57342338925793 bayes_pls_golite062009
U2 snRNA binding 1.09350203162237 bayes_pls_golite062009
protein binding 1.05805521997665 bayes_pls_golite062009
transcription factor activity 0.894914712180715 bayes_pls_golite062009
sequence-specific DNA binding 0.327072171076297 bayes_pls_golite062009
mRNA 3'-UTR binding 0.229644510503376 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [331-470]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGMPGQMMTQ QQIAAATGAA IPGQMMTPQQ IAAQYPYAYQ QMGYWYPPAT YPTTQMQTQY  60
   61 MQQGYYPYAY PTSAQQAGGV PCIQFSAAGY RMVPPNVAWG VPGTVVPGVT AAAASAAAAA 120
  121 NGSLAPQMMY SAAMPQYQTQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.30103
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

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