YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: orb-PD, orb-PB
Organism: Drosophila melanogaster
Length: 913 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for orb-PD, orb-PB.

Description E-value Query
Range
Subject
Range
orb-PA, FBpp0306565 - The gene oo18 RNA-binding protein is referred to in FlyBase by the symbol Dmel\orb (CG10868, FBgn000...
397.0 [0..78] [913..80]

Back

Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGVEKPYVV EPAMAVAQDS FEFGSNGDGS STNSHTSNAS SKDLGRLTSG DGAQNFAQDS  60
   61 SANSIDQDST DNTNSDCN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [79-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PITLNDLLGL CGASTANEVV GTGQTPSTSA PILGAGGGGR ANGVTAGAAT ATGVGVGAGG  60
   61 TLPGPGVPSI QGGGGGGVVG QQTNAS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.0
Match: 2ihxB
Description: No description for 2ihxB was found.

Predicted Domain #3
Region A:
Residues: [165-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CNTSAANPSA SFGGNGSSSD VNNLLLASAA AAAAAAAGDG AQLSANAAAY APLTPSSTHS  60
   61 SASPGTKSNF DYFQFENVAQ SNPLKAFQRT NI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [257-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFDCSAPLSP STPTSIYNRS FHSSPLVSDS SNSSSGIGLS MDSINMFYNQ QQQQQQPEQQ  60
   61 GYTSLGNSMG SGLGLSLANA STRSNSPESQ NSSNSTTEQN LLDMINLLSV NSNKIPHQQQ 120
  121 QQQQQQQQQQ QQQQQNQQQL QVQQQHQLQQ QFVNLNRNYE QQISANLGSQ QHGFEHNGVG 180
  181 VGASSSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [444-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NENCFSQYNL ENITSVDMEL AKLQNLQRIN TLKLLHAQAQ QMPLINQLLQ SYAGNAIGSV  60
   61 GGSNLGNLMS AGGSSLMTEM AGNVGGIITT NDGHLDRVAK FYKSSAALCD ATCT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [558-782]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WSGHLPPRSH RMLNYSPKVF LGGIPWDISE QSLIQIFKPF GSIKVEWPGK EQQAAQPKGY  60
   61 VYIIFESDKQ VKALLSACVL QVDDSHCGRN YFFKISSRRI KSKDVEVIPW IIADSNFVRS 120
  121 SSQKLDPTKT VFVGALHGKL TAEGLGNIMD DLFDGVLYAG IDTDKYKYPI GSGRVTFSNF 180
  181 RSYMKAVSAA FIEIRTTKFT KKVQVDPYLE DALCSICGVQ HGPYY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.154902
Match: 1pgzA
Description: Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.63987691433124 bayes_pls_golite062009
nucleic acid binding 3.64594243387558 bayes_pls_golite062009
mRNA binding 3.54495985180603 bayes_pls_golite062009
binding 3.00411894202318 bayes_pls_golite062009
protein binding 2.17260848225967 bayes_pls_golite062009
1.71820051628117 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 0.862661444935922 bayes_pls_golite062009
transcription regulator activity 0.737458867828906 bayes_pls_golite062009
DNA binding 0.691258294213766 bayes_pls_golite062009
mRNA 3'-UTR binding 0.599389001184667 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
sequence-specific DNA binding 0.366758605553422 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009
transcription activator activity 0.119266921032347 bayes_pls_golite062009
structural molecule activity 0.0829058000493267 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [783-913]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CRELSCFRYF CRSCWQWQHS CDIVKNHKPL TRNSKSQSLV GIGPSSSNVS LPFSGQRSIR  60
   61 DNRMGNGQHQ QHQQHQYQQQ KHRQLQEYSQ PHSLNVMGNS GAANAAATSM VTLQQRQIHK 120
  121 VRIQRQQHQA I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.045757
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle