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View Structure Prediction Details

Protein: Rpn7-PA
Organism: Drosophila melanogaster
Length: 389 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Rpn7-PA.

Description E-value Query
Range
Subject
Range
gi|114587651 - gi|114587651|ref|XP_520898.2| PREDICTED: proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 ...
288.0 [0..1] [389..219]

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Predicted Domain #1
Region A:
Residues: [1-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAENLEEQG LEKNPNLELA QTKFLLTLAE YKQDAALKAK LLEAIRTENM APWYEHICSE  60
   61 LGWTVDKDLL ARMKENNRVE VEQLDAAIED AEKNLGEMEV REANLKKSEY LCRIGDKAAA 120
  121 ETAFRKTYEK TVSLGHRLDI VFHLIRLGLF YLDHDLITRN IDKAKYLIEE GGDWDRRNRL 180
  181 KVYQGVYSVA VRDFKAAATF FLDTVSTFTS YELMDYPTFV RYTVYVAMIA LPRNELRDKV 240
  241 IKGSEIQEVL HGLPDVKQFL FSLYNCQYEN FYVHLA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.07
Match: 1qqeA
Description: Vesicular transport protein sec17
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 2.802999698299 bayes_pls_golite062009
binding 2.45002000313605 bayes_pls_golite062009
protein binding 1.41340296563325 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.499034250223658 bayes_pls_golite062009
small conjugating protein ligase activity 0.447205684237625 bayes_pls_golite062009
nucleic acid binding 0.437277381081288 bayes_pls_golite062009
enzyme binding 0.335436488591595 bayes_pls_golite062009
transcription regulator activity 0.326419413972955 bayes_pls_golite062009
DNA binding 0.186035324819401 bayes_pls_golite062009
signal sequence binding 0.0263114188894915 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [277-389]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVEKQLRLDY LIHPHYRYYV REMRILGYTQ LLESYRSLTL QYMAESFGVT VEYIDQELAR  60
   61 FIAAGRLHAK VDRVGGIVET NRPDNKNWQY QATIKQGDLL LNRIQKLSRV INI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.50995556050336 bayes_pls_golite062009
nucleic acid binding 3.38144578566524 bayes_pls_golite062009
binding 3.33026160538031 bayes_pls_golite062009
DNA binding 3.30822066787723 bayes_pls_golite062009
transcription factor activity 2.60537570879007 bayes_pls_golite062009
hydrolase activity 2.30467124306022 bayes_pls_golite062009
sequence-specific DNA binding 1.32971938164691 bayes_pls_golite062009
transcription activator activity 1.08566311616647 bayes_pls_golite062009
transcription repressor activity 0.95491822926452 bayes_pls_golite062009
protein binding 0.653872239015235 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.505349137311395 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.42135864069093 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.136726704233672 bayes_pls_golite062009
small conjugating protein ligase activity 0.118016217031359 bayes_pls_golite062009

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