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View Structure Prediction Details

Protein: slou-PA
Organism: Drosophila melanogaster
Length: 659 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for slou-PA.

Description E-value Query
Range
Subject
Range
gi|113416398 - gi|113416398|ref|XP_001131587.1| PREDICTED: similar to gamma-aminobutyric acid A receptor, epsilon ...
150.0 [0..6] [658..45]

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Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVMLQSPAQK ASDSASAQNT AVGGLMSPNS NPDSPKSNTS PDVASADSVV SGTGGGSTPP  60
   61 AAKIPKFIIS ANGAAVAGKQ EQELRYSLER LKQMSSESGS LLSRLSPLQE DSQDKEKPNH 120
  121 NN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [123-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNSLTNHNAN SNTRRSQSPP ASVGSVSFSS PAQQRKLLEL NAVRHLARPE PLQHPHAALL  60
   61 QQHPHLLQNP QFLAAAQQHM HHHQHQHHQH PAHPHSHQHP HPHPHPHPHP HPSAVFHLRA 120
  121 PSSSSTAPPS PATSPLSPPT SPAMHSDQQM SPPIAPPQNP PHSSQPPQQQ QVAAPSDMDL 180
  181 ERIKLVAAVA ARTTQASSTS ALASASNSVS NASISISN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [341-545]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSGSPSGRD LSDYGFRIQL GGLAAAAAAA AATSRQIAAA TYARSDTSEE LNVDGNDEDS  60
   61 NDGSHSTPSV CPVDLTRSVN SSAAANPSSA STSASSDRDA ATKRLAFSVE NILDPNKFTG 120
  121 NKLPSGPFGH PRQWSYERDE EMQERLDDDQ SEDMSAQDLN DMDQDDMCDD GSDIDDPSSE 180
  181 TDSKKGGSRN GDGKSGGGGG GGSKP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [546-659]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRARTAFTYE QLVSLENKFK TTRYLSVCER LNLALSLSLT ETQVKIWFQN RRTKWKKQNP  60
   61 GMDVNSPTIP PPGGGSFGPG AYASGLLYSH AVPYPPYGPY FHPLGAHHLS HSHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.221849
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
protein binding 1.88087411289001 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 1.04132983826241 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle