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View Structure Prediction Details

Protein: Pros28.1A-PA
Organism: Drosophila melanogaster
Length: 249 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pros28.1A-PA.

Description E-value Query
Range
Subject
Range
PSA7L_MOUSE - Proteasome subunit alpha type-7-like OS=Mus musculus GN=Psma8 PE=1 SV=1
270.0 [0..1] [248..1]
gi|116283481 - gi|116283481|gb|AAH14999.1| PSMA7 protein [Homo sapiens]
266.0 [0..5] [240..3]
PSA7L_MACFA - Proteasome subunit alpha type-7-like OS=Macaca fascicularis GN=PSMA7L PE=2 SV=1
264.0 [0..1] [232..1]
gi|157820507, gi... - gi|157820507|ref|NP_001102354.1| hypothetical protein LOC364814 [Rattus norvegicus], gi|149015674|gb...
263.0 [0..1] [234..1]
PSA7_BOVIN - Proteasome subunit alpha type-7 OS=Bos taurus GN=PSMA7 PE=1 SV=1
262.0 [0..5] [232..3]
gi|46254564 - gi|46254564|gb|AAS86255.1| testes-specific alpha4-t1 proteasome subunit [Drosophila mauritiana]
262.0 [0..1] [249..1]

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Predicted Domain #1
Region A:
Residues: [1-249]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSRYGRALT IFSPDGHLLQ VEYAQEAVRK GSTAVGVRGA NCVVLGVEKS SVSEMQEDRT  60
   61 VRKISMLDRH VALAFAGLTA DARILINRGQ VECQSHRLNF ENQVTLEYIT RYLAQLKQKY 120
  121 TQCNGRRPFG ISCLIGGIDA DGSARLFHTE PSGIFHEYKA TATGRWANTV REFFEKAYSD 180
  181 HEVTTKCDAI KLAMRALLEV TQMSQMRLEV AVLENGKPMK MLDSVVISEI VKIVQNEKEL 240
  241 QAKAHKMKR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.045757
Match: 1iruD
Description: Proteasome alpha subunit (non-catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endopeptidase activity 6.91642761177919 bayes_pls_golite062009
peptidase activity 6.84511694091156 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.5973571808298 bayes_pls_golite062009
hydrolase activity 4.47652590304822 bayes_pls_golite062009
threonine-type endopeptidase activity 2.98214579292788 bayes_pls_golite062009
threonine-type peptidase activity 2.98214579292788 bayes_pls_golite062009
binding 1.75265921676176 bayes_pls_golite062009
nucleic acid binding 1.39216781236247 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle