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View Structure Prediction Details

Protein: sqz-PA
Organism: Drosophila melanogaster
Length: 535 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sqz-PA.

Description E-value Query
Range
Subject
Range
gi|76651068 - gi|76651068|ref|XP_887912.1| PREDICTED: similar to zinc finger protein 192 isoform 5 [Bos taurus]
713.0 [0..3] [535..363]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELPTAPNG VPSGDYLHRS IDQLRSLGHL TTAQLVHDYK PFNISEFRQN VAERLDYSLK  60
   61 NGLVQHQQQM VMEQQPHPDQ QQQQHLHHPQ QQQHPPQLKV SYSAPNSPPT PHEQQEQKYD 120
  121 PNRSPPRQQM SSASGSGSNG SSPEEESRRG DGDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.221849
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #2
Region A:
Residues: [155-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKPYKCGSCS KSFANSSYLS QHTRIHLGIK PYRCEICQRK FTQLSHLQQH IRTHTGDKPY  60
   61 KCRHAGCPKA FS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.78
Match: 1a1hA
Description: ZIF268
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [227-319]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLSNLQSHSR CHQTDKPFKC NSCYKCFSDE MTLLEHIPKH KDSKHLKTHI CNLCGKSYTQ  60
   61 ETYLQKHLQK HAEKAEKQQH RHTAQVAAHQ QHV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.69897
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
nucleic acid binding 4.28215395396923 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.31369346002275 bayes_pls_golite062009
transcription activator activity 2.19952417915035 bayes_pls_golite062009
transcription repressor activity 1.64349785387632 bayes_pls_golite062009
sequence-specific DNA binding 1.42975942698743 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
chromatin binding 1.37132088004982 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.0497955246512 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
transcription corepressor activity 0.10558148421807 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [320-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PASGIGLNLQ RQAMNDVNAA YWAKMGADSA AASLAEAIQQ QLPQAGGQPY GNFASLQQQH  60
   61 QQQQQELLHH QRLADTPGHS HSPHEEAAGE DLVLRQSTPQ HHLQQQQQQQ Q

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [431-535]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQAQQQQQA QHQPSPGPGN SAFTPLSATV APPPHLQQHR GPPGSAAAYL YQQNAAAAAA  60
   61 AFPTQLISLH QIRNYAHQPG AAGLIAGDHL ALGLSAVNAA KEKAQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle