YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: ss-PA
Organism: Drosophila melanogaster
Length: 884 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ss-PA.

Description E-value Query
Range
Subject
Range
gi|3132524 - gi|3132524|gb|AAD09205.1| Ahr homolog spineless; bHLH-PAS transcription factor spineless [Drosophila...
429.0 [0..1] [884..1]

Back

Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQLGTVYAT KRRRRNGKSL KPPPKDGVTK SNPSKRHRER LNAELDLLAS LLPFEQNILS  60
   61 KLDRLSILRL SVSYLRTKSY FQVVMHKDKE DNGVLPHIHA HDGYRTRELG A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1am9A
Description: SREBP-1a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.39500382187264 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 2.22731296211498 bayes_pls_golite062009
protein binding 1.59929864805879 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
promoter binding 0.68523657427264 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [112-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FEHGLLDGDM FLQALNGFLM ILTCEGEVFF ATHSIESYLG FHQSDIVHQS VYELVHSEDR  60
   61 EELQRQLLWN SFLPADMSSM QLAETLAPDK ALYLERSFTV RFRCLLDNTS GFLRLDIRGR 120
  121 IKVLHGQNRK TEEPPLALFA YCTPFGPPSL LEIPHKENMF KSKHKLDFSL VSMDQRGKHI 180
  181 LGYADAELVN MGGYDLVHYD DLAYVASAHQ ELLKTGASGM IAYRYQKKDG EWQWLQTSSR 240
  241 LVYKNSKPDF VICTHRQLMD EEGHDLLGKR TMDFKVSYLD TGLASTYFSE ADQLVVPPST 300
  301 SPTAHALPPP VTPTRPNRRY KTQLRDFLST CRSKRKLQQQ NQPQTQQTSP LGGQVGSPAP 360
  361 AVAVEY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.0
Match: 1wa9A
Description: Crystal Structure of the PAS repeat region of the Drosophila clock protein PERIOD
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [478-661]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPDPAAAVAA AYSNLNPMYT TSPYASAADN LYMGSSMPAN AFYPVSENLF HQYRLQGAVG  60
   61 GYYTDYPHSG APASAYVANG FLSYDGYAIA SKADEKWQET GKYYSGYSSG YGSPTSTPQV 120
  121 RKQIPLKTPK SSPQVMEVIS CSSDGPSPVG GATPNGVGSV TPKVELAGTT AAAAAGQDPY 180
  181 ERQT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [662-884]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLMWGTTHSS GVPLNSHGGR TGAGNPASPQ RSTPLGNGLG YASANNNNND LEPATAAKWN  60
   61 GTKELPGKSG SASTPESYQM QHDDSGLYSA SSHTTSPQQQ QQQQLQQSQR GVGSNVSAPS 120
  121 SSLTSTGTDQ QAVHPSSCHQ QQQQQQQQHH HAHPHPHSHH HHHHHHHHET AHQHSSEVWT 180
  181 PASYTQYSQY FTYHHPHPHP HHPSAGGGGH VPAQSHHLHH GHR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle