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View Structure Prediction Details

Protein: Art3-PA
Organism: Drosophila melanogaster
Length: 516 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Art3-PA.

Description E-value Query
Range		 Subject
Range
ANM3_RAT - Protein arginine N-methyltransferase 3 OS=Rattus norvegicus GN=Prmt3 PE=1 SV=1
 386.0 [0..19] [515..16]

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Predicted Domain #1
Region A:
Residues: [1-110] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDTEVNDNT TEEEPVKEAP EVPANSSSDE DEYDDIDDDD EPMDEGDELT TCLFCTETSA  60
   61 NISVAIDHLD ARHKVNLSQL QRKFEMDQYS FIKLINYIRA KKISAEQLLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.0
Match: 1wirA
Description: Solution structure of the C2H2 zinc finger domain of the protein arginine N-methyltransferase 3 from Mus musculus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 2.97176528779183 bayes_pls_golite062009
binding 2.90895627801407 bayes_pls_golite062009
DNA binding 2.78082210591574 bayes_pls_golite062009
transcription regulator activity 2.76424128832177 bayes_pls_golite062009
chromatin binding 2.17816148863289 bayes_pls_golite062009
transcription factor activity 1.86916601862986 bayes_pls_golite062009
transcription activator activity 1.80788203686439 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.03479741823043 bayes_pls_golite062009
sequence-specific DNA binding 1.03263180686496 bayes_pls_golite062009
protein binding 0.905022998164426 bayes_pls_golite062009
histone binding 0.687710658383448 bayes_pls_golite062009
RNA binding 0.488467613481041 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.47431986827149 bayes_pls_golite062009
transcription repressor activity 0.471566310582559 bayes_pls_golite062009
transcription factor binding 0.33284536030284 bayes_pls_golite062009
cytoskeletal protein binding 0.311339098303136 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
signal transducer activity 0.132157047337325 bayes_pls_golite062009
molecular transducer activity 0.132157047337325 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [111-185] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEHPLWQDEK YLQPGEYEPW LCYDYEVLKT DGAPTQPSVL ELQQRIAEQS QLLQQANEDM  60
   61 ERMRNDYKAL LQKVH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.39794
Match: 1ufkA
Description: Crystal structure of TT0836
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [186-516] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADGEPKGSDQ SVPRNNVCLD NEYFKSYAHF GIHHEMLSDK VRTSTYRASL LQNEAVVRGK  60
   61 TVLDVGCGTG ILSIFASKAG AARVVGIDNS DIVYTAMDII RKNKVENVEL IKGRLEDTDL 120
  121 PETKYDIIIS EWMGYFLLYE SMLDSIIYAR ENHLNPNGII LPSRCTLSLL GYGDDTLYAD 180
  181 EVEFWSNVYE VDMSDLRKQS IEEPLMQVVD AEFMLTEPEQ IANFDIMTVD MNYPNFTHQF 240
  241 SLKVTKPGRL SAFVGYFETL FELPSPVMFS TSPSATPTHW KQTVFFIENP QVVKEGDVIC 300
  301 GKITSRRHKE DVRGLSVDIE VFGKKHKYNV V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.39794
Match: 2fytA
Description: No description for 2fytA was found.
YRC Informatics Platform - Version 3.0
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