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View Structure Prediction Details

Protein: Su(fu)-PA
Organism: Drosophila melanogaster
Length: 468 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Su(fu)-PA.

Description E-value Query
Range
Subject
Range
gi|1199514, gi|1... - gi|1236919|gb|AAA93016.1| Method: conceptual translation supplied by author [Drosophila melanogaster...
772.0 [0..1] [468..1]

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Predicted Domain #1
Region A:
Residues: [1-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEANLDKKP EVKPPPGLKA IIDHLGQVYP NQPNPLQVTT LLKYWLGGQD PLDYISMYNY  60
   61 PGDVDRNVPP HWHYISFGLS DLHGDERVHL REEGVTRSGM GFELTFRLAK TEIELKQQIE 120
  121 NPEKPQRPPT WPANLLQAIG RYCFQTGNGL CFGDNIPWRK SLDGSTTSKL QNLLVAQDPQ 180
  181 LGCIDTPTGT VDFCQIVGVF DDELEQASRW NGRGVLNFLR QDMQTGGDWL VTNMDRQMSV 240
  241 FEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.0
Match: 1m1lA
Description: Human Suppressor of Fused (N-terminal domain)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.65237304297126 bayes_pls_golite062009
transcription repressor activity 2.47003360530383 bayes_pls_golite062009
binding 2.41295334316774 bayes_pls_golite062009
transcription corepressor activity 1.84010667745013 bayes_pls_golite062009
protein binding 1.12780009486864 bayes_pls_golite062009
transcription factor binding 0.95220109251721 bayes_pls_golite062009
signal transducer activity 0.94580551292628 bayes_pls_golite062009
molecular transducer activity 0.94580551292628 bayes_pls_golite062009
transcription cofactor activity 0.75239107568956 bayes_pls_golite062009
identical protein binding 0.162521380543051 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [244-337]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPETLLNLQD DLEKQGSDLA GVNADFTFRE LKPTKEVKEE VDFQALSEKC ANDENNRQLT  60
   61 DTQMKREEPS FPQSMSMSSN SLHKSCPLDF QAQA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [338-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNCISLDGIE ITLAPGVAKY LLLAIKDRIR HGRHFTFKAQ HLALTLVAES VTGSAVTVNE  60
   61 PYGVLGYWIQ VLIPDELVPR LMEDFRSAGL DEKCEPKERL ELEWPDKNLK LIIDQPEPVL 120
  121 PMSLDAAPLK M

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle