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View Structure Prediction Details

Protein: sage-PB
Organism: Drosophila melanogaster
Length: 178 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sage-PB.

Description E-value Query
Range
Subject
Range
gi|17946262 - gi|17946262|gb|AAL49171.1| RE59356p [Drosophila melanogaster]
137.0 [0..1] [178..1]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGYEKEAHN MGLLPPTYSV IPQPVSMWHA GQVATGSPVG LECNKPSELV PPPMYMSYSG  60
   61 GSIANSTEVD IAKEHNPAWR EKA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [84-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQMEKDYRRT ACDRERTRMR DMNRAFDLLR SKLPISKPNG KKYSKIESLR IAINYINHLQ  60
   61 AMLRESSVGQ NGNGCCAWSG GSSSPYDNGN DHWGA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 1am9A
Description: SREBP-1a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
nucleic acid binding 4.75270293029792 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.48787404513864 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
protein binding 1.59929864805879 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 1.46304579811572 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle