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View Structure Prediction Details

Protein: Pbp95-PA
Organism: Drosophila melanogaster
Length: 721 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Pbp95-PA.

Description E-value Query
Range		 Subject
Range
gi|108880023, gi... - gi|157105712|ref|XP_001648992.1| hypothetical protein AaeL_AAEL004377 [Aedes aegypti], gi|108880023|...
 397.0 [0..29] [721..52]

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Predicted Domain #1
Region A:
Residues: [1-151] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDADDLRIN QQQLMDEISA LLQNTAKPSA ANALQLNQEL QRRLMQVRTK ILAMLQVVRA  60
   61 RFSRNEDILV RRLRPRSHFG PNSLNLSGAI LRKGTFRFKG NLFFRDIDGR SCPNNEDYEA 120
  121 RCHTEMFPTD FDMHSRHVWT LLDKKNVIMG I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 1guuA
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.57523737355937 bayes_pls_golite062009
DNA binding 2.7565055095762 bayes_pls_golite062009
nucleic acid binding 2.48097584527739 bayes_pls_golite062009
transcription factor activity 2.33198016659192 bayes_pls_golite062009
binding 2.21133851845856 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.14821760889085 bayes_pls_golite062009
sequence-specific DNA binding 0.37638337609693 bayes_pls_golite062009
protein binding 0.319330156880518 bayes_pls_golite062009
transcription repressor activity 0.20862059645422 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [152-232] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQQLLEHRAH STNALPSGSL KRKPIERHLS TLVSLLATAD SSFSIDWNQI STLDLEYRHS  60
   61 PYSCEAMWRV YLTPDLRRDD W

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [233-277] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPEEDETLLA VATANRMQNW ELIAASLDRR SDYQCFVRFH TALRF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.522879
Match: 1mbjA
Description: MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.57523737355937 bayes_pls_golite062009
DNA binding 2.7565055095762 bayes_pls_golite062009
nucleic acid binding 2.48097584527739 bayes_pls_golite062009
transcription factor activity 2.33198016659192 bayes_pls_golite062009
binding 2.21133851845856 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.14821760889085 bayes_pls_golite062009
sequence-specific DNA binding 0.37638337609693 bayes_pls_golite062009
protein binding 0.319330156880518 bayes_pls_golite062009
transcription repressor activity 0.20862059645422 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [278-444] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLEPKNSHRW SEEDNDKLRA IVDRNTANSV INWKKVVEYF PDKSKSTLIG RYYYVLHPSI  60
   61 SHEPFTTKED MMLFAAVEEY NGKFHCFPRS LFPNRSLTQL RTRYHNVLAQ RNKTDSWSVQ 120
  121 DDTRLMSFVT QYGASQWLNC ATFLGNHTRT SCRTRFLVIK KFLEQNP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.09691
Match: 1h88C
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.57523737355937 bayes_pls_golite062009
DNA binding 2.7565055095762 bayes_pls_golite062009
nucleic acid binding 2.48097584527739 bayes_pls_golite062009
transcription factor activity 2.33198016659192 bayes_pls_golite062009
binding 2.21133851845856 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.14821760889085 bayes_pls_golite062009
sequence-specific DNA binding 0.37638337609693 bayes_pls_golite062009
protein binding 0.319330156880518 bayes_pls_golite062009
transcription repressor activity 0.20862059645422 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [445-554] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAKVEDLPRR RSKKVSLVNS DNWAQRLQEW QEDPESLVND NPPKGTRVRG PKSKKARIER  60
   61 QAESFSRLSK VDIEFCNFFK FSYNLTLSTP KTFPVPKDVY NLAYVIRALA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [555-721] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKPPIRPSLL QNIFMPNDVL KCYNSMIRNL PDEEGDMKSP LLPPNWSTMM GFRALCILSG  60
   61 DCRKDTETRS FEYNESLPPI QLFRKRLQAL FYRTTLLSRL ESQLFTDLPS ALVSLPRPKH 120
  121 DYAKMGTHVE LIDPEPAPQN DLKSEPLSEN EVINTVKQEL EMEYTVP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle