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View Structure Prediction Details

Protein: tub-PC
Organism: Drosophila melanogaster
Length: 462 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tub-PC.

Description E-value Query
Range
Subject
Range
gi|158751, gi|103435 - gi|158751|gb|AAA28994.1| tube protein, pir||A33170 tube protein - fruit fly (Drosophila melanogaster...
394.0 [0..1] [462..1]

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Predicted Domain #1
Region A:
Residues: [1-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYGWNGCGM GVQVNGSNGA IGLSSKYSRN TELRRVEDND IYRLAKILDE NSCWRKLMSI  60
   61 IPKGMDVQAC SGAGCLNFPA EIKKGFKYTA QDVFQIDEAA NRLPPDQSKS QMMIDEWKTS 120
  121 GKLNERPTVG VLLQLLVQAE LFSAADFVAL DFLNESTPAR PVDGPGALIS LELLEEEMEV 180
  181 DNEGLSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.69897
Match: 1d2zB
Description: Tube death domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.81925838257497 bayes_pls_golite062009
protein binding 2.45473206123776 bayes_pls_golite062009
transmembrane receptor activity 1.66783807193588 bayes_pls_golite062009
receptor activity 1.49139108045528 bayes_pls_golite062009
tumor necrosis factor binding 0.568964907907048 bayes_pls_golite062009
death receptor activity 0.402285252819743 bayes_pls_golite062009
tumor necrosis factor receptor activity 0.201711780440556 bayes_pls_golite062009
signal transducer activity 0.201651915574531 bayes_pls_golite062009
molecular transducer activity 0.201651915574531 bayes_pls_golite062009
protein domain specific binding 0.151782936408674 bayes_pls_golite062009
cytokine binding 0.0519010687665362 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [188-462]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYQSSTATLG ADAQGSVGLN LDNFEKDIVR RDKSVPQPSG NTPPIAPPRR QQRSTTNSNF  60
   61 ATLTGTGTTS TTIPNVPNLT ILNPSEQIQE PVLQPRPMNI PDLSILISNS GDLRATVSDN 120
  121 PSNRTSSTDP PNIPRITLLI DNSGDVNSRP NHAPAKASTA TTSTASSNNL PMISALNISK 180
  181 GSRETLRPES RSSSSSLSKD DDDDNDGEED GEEEYPDAFL PNLSNSEQQS SNNDSSLTTV 240
  241 TGTSGDNSFE LTNDSSSTSN DDYACNIPDL SELQQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle