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View Structure Prediction Details

Protein: CG14641-PA
Organism: Drosophila melanogaster
Length: 418 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG14641-PA.

Description E-value Query
Range
Subject
Range
gi|54639378|gb|E... - GA13140-PA [Drosophila pseudoobscura], GA13140 [Drosophila pseudoobscura pseudoobscura]
gi|125777509, gi... - gi|54639378|gb|EAL28780.1| GA13140 [Drosophila pseudoobscura pseudoobscura], gi|125777509|ref|XP_001...
gi|195156856, gi... - gi|195156856|ref|XP_002019312.1| GL12337 [Drosophila persimilis], gi|194115903|gb|EDW37946.1| GL1233...
356.0 [0..1] [416..1]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMSKTTNTY NRQNWEDAEF PILCQTCLGD NPYVRMIKER FGKECKICTR PFTIFRWCPG  60
   61 ARMRFKKTEI CQTCARLKNV CQTCLLDLEY GL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [93-205]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIQVRDAALK VADNMPQSDV NKEYYIQNID AQLQDGDGTE AAGAVGRSLA ANEMLSKLAR  60
   61 TAPYYKRNRP HICSFWVKGE CKRGEECPYR HDKPNEPDDP LCEQNIKDRY YGR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.522879
Match: 1x4bA
Description: Solution structure of RRM domain in Heterogeneous nuclear ribonucleaoproteins A2/B1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [206-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDPVAEKIMK RAASLPTLEP PEDRNITTLY VGNLPEEITE PELRDQFYQF GEIRSIALVP  60
   61 RQQCAFVQYT KRNAAELAAE RTFNKLVIQG RKVSIKWAHS Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 2ytcA
Description: No description for 2ytcA was found.

Predicted Domain #4
Region A:
Residues: [307-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKQGTAAKTD RRFDLAGIPP PSAKPNDYFN LRQEQINVMP AGMKLHQLPS NLVPASAYQM  60
   61 YGQPTYAAPY GNATSTALSS SGVNLDSISI PPPPGQVPYP SQDASRMGAV KK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle