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View Structure Prediction Details

Protein: CG14641-PA
Organism: Drosophila melanogaster
Length: 418 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG14641-PA.

Description E-value Query
Range
Subject
Range
gi|54639378|gb|E... - GA13140-PA [Drosophila pseudoobscura], GA13140 [Drosophila pseudoobscura pseudoobscura]
gi|125777509, gi... - gi|54639378|gb|EAL28780.1| GA13140 [Drosophila pseudoobscura pseudoobscura], gi|125777509|ref|XP_001...
gi|195156856, gi... - gi|195156856|ref|XP_002019312.1| GL12337 [Drosophila persimilis], gi|194115903|gb|EDW37946.1| GL1233...
356.0 [0..1] [416..1]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMSKTTNTY NRQNWEDAEF PILCQTCLGD NPYVRMIKER FGKECKICTR PFTIFRWCPG  60
   61 ARMRFKKTEI CQTCARLKNV CQTCLLDLEY GL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.489 N/A N/A c.52.2 tRNA splicing endonuclease, C-terminal domain
View Download 0.437 N/A N/A d.58.2 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
View Download 0.414 N/A N/A c.52.2 tRNA splicing endonuclease, C-terminal domain
View Download 0.399 N/A N/A c.52.1 Restriction endonuclease-like
View Download 0.351 N/A N/A b.36.1 PDZ domain-like

Predicted Domain #2
Region A:
Residues: [93-205]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIQVRDAALK VADNMPQSDV NKEYYIQNID AQLQDGDGTE AAGAVGRSLA ANEMLSKLAR  60
   61 TAPYYKRNRP HICSFWVKGE CKRGEECPYR HDKPNEPDDP LCEQNIKDRY YGR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.522879
Match: 1x4bA
Description: Solution structure of RRM domain in Heterogeneous nuclear ribonucleaoproteins A2/B1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
transcription regulator activity 1.92450390013691 bayes_pls_golite062009
DNA binding 1.8021593476478 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
transcription factor activity 1.15127506309683 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [206-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDPVAEKIMK RAASLPTLEP PEDRNITTLY VGNLPEEITE PELRDQFYQF GEIRSIALVP  60
   61 RQQCAFVQYT KRNAAELAAE RTFNKLVIQG RKVSIKWAHS Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 2ytcA
Description: No description for 2ytcA was found.

Predicted Domain #4
Region A:
Residues: [307-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKQGTAAKTD RRFDLAGIPP PSAKPNDYFN LRQEQINVMP AGMKLHQLPS NLVPASAYQM  60
   61 YGQPTYAAPY GNATSTALSS SGVNLDSISI PPPPGQVPYP SQDASRMGAV KK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.154902
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle