YRC Public Data Repository - Protein Structure Prediction

Protein:	CG4842-PA
Organism:	Drosophila melanogaster
Length:	259 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG4842-PA.

Description	E-value	Query Range	Subject Range
gi\|146296617, gi... - gi\|82501013\|ref\|ZP_00886394.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Caldicellulosiruptor sacc...	274.0	[0..3]	[245..4]
FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima GN=fabG PE=3 SV=1 FABG_THEMA - 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...	274.0	[0..1]	[245..1]
gi\|18310052, gi\|... - gi\|18310052\|ref\|NP_561986.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens st...	272.0	[0..3]	[245..2]
gi\|115250215, gi... - gi\|126698778\|ref\|YP_001087675.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile 6... gi\|255306086 - gi\|255306086\|ref\|ZP_05350258.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile AT... gi\|255100197 - gi\|255100197\|ref\|ZP_05329174.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC...	270.0	[0..1]	[246..2]
gi\|255313843 - gi\|255313843\|ref\|ZP_05355426.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255516524 - gi\|255516524\|ref\|ZP_05384200.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255649624 - gi\|255649624\|ref\|ZP_05396526.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|254974717 - gi\|254974717\|ref\|ZP_05271189.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile QC... gi\|255092105 - gi\|255092105\|ref\|ZP_05321583.1\| 3-oxoacyl-[acyl-carrier protein] reductase [Clostridium difficile CI... gi\|90575404, gi\|... - gi\|90575404\|ref\|ZP_01231888.1\| hypothetical protein CdifQ_02001165 [Clostridium difficile QCD-32g58]...	269.0	[0..1]	[246..2]
gi\|89098688, gi\|... - gi\|89098688\|ref\|ZP_01171570.1\| beta-ketoacyl-acyl carrier protein reductase [Bacillus sp. NRRL B-149...	268.0	[0..1]	[245..1]
gi\|168210762, gi... - gi\|170711222\|gb\|EDT23404.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens B st... gi\|110675446, gi... - gi\|110800799\|ref\|YP_695772.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens A... gi\|170660709, gi... - gi\|170660709\|gb\|EDT13392.1\| 3-oxoacyl- reductase [Clostridium perfringens E str. JGS1987], gi\|168207...	268.0	[0..3]	[245..2]
gi\|110803752, gi... - gi\|110803752\|ref\|YP_698460.1\| 3-ketoacyl-(acyl-carrier-protein) reductase [Clostridium perfringens S...	267.0	[0..3]	[245..2]
gi\|91184216, gi\|... - gi\|91217712\|ref\|ZP_01254669.1\| putative 3-oxoacyl-[acyl-carrier protein] reductase [Psychroflexus to...	265.0	[0..3]	[245..11]
gi\|158320488, gi... - gi\|158320488\|ref\|YP_001512995.1\| 3-oxoacyl-(acyl-carrier-protein) reductase [Alkaliphilus oremlandii...	263.0	[0..1]	[243..1]

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Predicted Domain #1

Region A:
Residues: [1-259]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLAGKNVVY LGGFGGIGQK CVQELLQRPI KALAIFDLNA NEQLLAKWKS QHPDTDVFYH  60
   61 KLDITQKSDI DAAYKATAER FGHFDVVVNG SGLMNDRLVE LTIQINLLGV INSTLTALEY 120
  121 MDKAKGGKGG LIVNISSVAG LQPTAIMAIY SAAKTGVTTF TRAMANPYFY AHSGVGFLTI 180
  181 CPGFTDTGLL EDIGNKTTFT YDTPMLAMFN RVKRQKAEDC ARNLVSAIET SKNGTVLMLE 240
  241 MGETTEVDMP VMWKPQLDN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1a4uA
Description:	Drosophila alcohol dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
NAD or NADH binding	2.13234420851832	bayes_pls_golite062009
catalytic activity	1.79741889688267	bayes_pls_golite062009
oxidoreductase activity	1.69771604880532	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	1.54163865723354	bayes_pls_golite062009
ethanol binding	1.50520365612357	bayes_pls_golite062009
retinol binding	1.31161238631275	bayes_pls_golite062009
fatty acid synthase activity	1.23679054027553	bayes_pls_golite062009
alcohol binding	1.22695269806324	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] reductase activity	0.604742541607263	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	0.54910246066113	bayes_pls_golite062009
NADPH:quinone reductase activity	0.520319547841251	bayes_pls_golite062009
all-trans retinal binding	0.445128389050035	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.418775403210681	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.32207755075663	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	0.196071455245233	bayes_pls_golite062009
binding	0.195230307786433	bayes_pls_golite062009
benzaldehyde dehydrogenase activity	0.0870360798161197	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: