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View Structure Prediction Details

Protein: rib-PA, FBpp0303090
Organism: Drosophila melanogaster
Length: 661 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rib-PA, FBpp0303090.

Description E-value Query
Range
Subject
Range
KLHL2_MOUSE - Kelch-like protein 2 OS=Mus musculus GN=Klhl2 PE=1 SV=1
194.0 [0..2] [315..13]

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Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGPTAPVAS SGEVGQTYCL RWNNHQTNLV QILHALHEVG SYVDCSLVVD DEQFQAHRVV  60
   61 LAANSPYFQH ILKDVPQDHC SIILPGVKGF EIAALLQYMY TGETTVTKSQ EPEILRTAKE 120
  121 LQVKGLYDNL MKFNHASVTP TSSSGAGGAK PQNGSASNHS SSVISTSTHI SPSAAISSSC 180
  181 SPPPPPQFGY 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.522879
Match: 2nn2A
Description: No description for 2nn2A was found.

Predicted Domain #2
Region A:
Residues: [191-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPGYSHYPQQ QPMSASQIPA GEAPLTPTQA TPHSAASGAG EAGGQWPLTP SAAAAMLNSV  60
   61 YESAADMNPL KRKKLSAISS MLLSGNRDTP ILRNVLAQAN PADSSQPGPM NANGEKTPTH 120
  121 PHQNTQLPAG LGVSGGE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [328-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNHSFNGSDY GGDKEPLSPY TDRSFEEETG QSGGKKPEWK RYKQYTRADM MCAIQAVREG  60
   61 MSALQASRKY GLPSRTLYDK VRKLNITTGR GTHRTPKR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.14
Match: 2cobA
Description: Solution structures of the HTH domain of human LCoR protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.86538715425734 bayes_pls_golite062009
DNA binding 4.40186699787632 bayes_pls_golite062009
nucleic acid binding 4.28652307290136 bayes_pls_golite062009
transcription factor activity 3.78935192723648 bayes_pls_golite062009
transcription repressor activity 3.3280771187468 bayes_pls_golite062009
sequence-specific DNA binding 3.25454589469681 bayes_pls_golite062009
transcription activator activity 2.92652250400688 bayes_pls_golite062009
binding 2.92574888336072 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.91588376840709 bayes_pls_golite062009
protein binding 1.84594855626241 bayes_pls_golite062009
chromatin binding 1.46954724788757 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.44773725829085 bayes_pls_golite062009
transcription corepressor activity 1.30723796612579 bayes_pls_golite062009
transcription factor binding 1.24678737091956 bayes_pls_golite062009
transcription cofactor activity 0.691780246385357 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [426-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPPGAESSQG FSYSAAAAAA AHNYGHGHGH HSEVKRDQKV DHVPAHHGMP PTIPPSAAAL  60
   61 LDHAFLQQAL ENRGGDMAGR EALHAMALAA AAHAAANRLS SS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [528-661]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAEMDQRSNG HGMRSPSPQG RHYPHEQEAM DLEMEKHEQN IIKRERDQDE REDADDEEDH  60
   61 EQEHVEDLSL ARKERPPSPY SPQPTEAGAG VIMHASSASA NGKDHVDYPS SPQFVPIGLK 120
  121 RELMEGEDAQ ARAD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle