YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Aats-cys-PA
Organism: Drosophila melanogaster
Length: 741 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Aats-cys-PA.

Description E-value Query
Range
Subject
Range
gi|26328991, gi|... - gi|31980754|ref|NP_038770.2| cysteinyl-tRNA synthetase [Mus musculus], gi|26328991|dbj|BAC28234.1| u...
483.0 [0..2] [741..94]

Back

Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRGQPAWQ APEAVDRPKL KLFNSLTRQK EDFVPLDGNN VTWYSCGPTV YDASHMGHAR  60
   61 SYISFDILRR ILSDYFGYNI HYVMNITDID DKIIRRARQN HLFDEYAAEA QK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.69897
Match: 1iq0A
Description: Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [113-638]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPLDELLGQQ KEVLQRFQDT CAKNTDPDKK IMLDKTLQRM NDAVEALTKA VGKGDEREIS  60
   61 EKRLLYLNEA KDPISDWLDS LKGAQINDNA VFEALPRYWE DQFHNDMKSL NILPPDVLTR 120
  121 VSEYVPQIVT FIQKIIDNGL AYAANNSVYF DVNGFDKREK HHYAKLVPEA YGDTKSLQEG 180
  181 EGDLSIAEDR LSEKRSANDF ALWKASKAGE PWWDSPWGKG RPGWHIECSA MASDIFGPTF 240
  241 DIHTGGVDLK FPHHDNELAQ SEAAFNESEW VKYFLHTGHL TIAGCKMSKS LKNFVTIQEA 300
  301 LKKHSATQLR LAFLLHSWKD TLDYSENTME MATQYEKFLN EFFLNVKDLT RHVLSEEPRR 360
  361 QFDAWTEVEA ALQKKFSNAQ VQVHASLCDN IDTRSALDAI RELVSVSNVY IRDNKTRLNS 420
  421 LLLRNVATYI TDLLHVFGAI SGPRGGIGFP VSGGSGAQAA GADLETTVLP YVQSLAEFRY 480
  481 LVREQAKTLK AFDILKLCDD LRDNVLPNLG VRLEDKDIGK YAVKLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.69897
Match: 1li5A
Description: Cysteinyl-tRNA synthetase (CysRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming aminoacyl-tRNA and related compounds 7.16276509815667 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.16276509815667 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.13957775963187 bayes_pls_golite062009
ligase activity 6.11211476973434 bayes_pls_golite062009
cysteine-tRNA ligase activity 5.23703961447809 bayes_pls_golite062009
isoleucine-tRNA ligase activity 3.76808520367507 bayes_pls_golite062009
glutamate-tRNA ligase activity 2.63681738794687 bayes_pls_golite062009
catalytic activity 2.37674226834122 bayes_pls_golite062009
methionine-tRNA ligase activity 2.01261843164558 bayes_pls_golite062009
tyrosine-tRNA ligase activity 1.88984817882585 bayes_pls_golite062009
tryptophan-tRNA ligase activity 1.14187887833901 bayes_pls_golite062009
arginine-tRNA ligase activity 1.13743634264647 bayes_pls_golite062009
nucleotidyltransferase activity 0.89131347796645 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.625793556381714 bayes_pls_golite062009
nucleic acid binding 0.369886886936128 bayes_pls_golite062009
RNA binding 0.306683553109855 bayes_pls_golite062009
glutamine-tRNA ligase activity 0.118292082006187 bayes_pls_golite062009
binding 0.090743795600025 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [639-741]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRDSLLRERE AKLAAEAEKA AEKERKKQAA AEAAAAKEAQ RRVNPKEMFL AETEKYSAFD  60
   61 ENGLPTHDKE GKEVSKGQIK KLQKLQQQQE QRYNEYLASI EKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.154902
Match: 1wz2A
Description: The crystal structure of Leucyl-tRNA synthetase and tRNA(leucine) complex
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle