| Protein: | arr-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1678 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for arr-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
1437.0 | [0..79] | [1674..13] |
|
Region A: Residues: [1-418] |
1 11 21 31 41 51
| | | | | |
1 MALEPYTKSA EIEPQLCQVI DNNEDVTTKA TKCTKSNSGV GWRQMLIGFL LICFGISNSW 60
61 QYKNVHMPSS SSLIASPPAS AFVNTPATLL FTTRHDIQVA NITRPTGGPQ IDVIVRDLAE 120
121 AMAIDFYYAK NLVCWTDSGR EIIECAQTNS SALQPLLRAP KQTVISTGLD KPEGLAMDWY 180
181 TDKIYWTDGE KNRIEVATLD GRYQKVLFWT DLDQPRAVAV VPARKLLIWT DWGEYPKIER 240
241 ASMDGDPLSR MTLVKEHVFW PNGLAVDLKN ELIYWTDGKH HFIDVMRLDG SSRRTIVNNL 300
301 KYPFSLTFYD DRLYWTDWQR GSLNALDLQT RELKELIDTP KAPNSVRAWD PSLQPYEDNP 360
361 CAHNNGNCSH LCLLATNSQG FSCACPTGVK LISANTCANG SQEMMFIVQR TQISKISL
|
| Detection Method: |  |
| Confidence: | 93.69897 |
| Match: | 1n7dA |
| Description: | Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor activity | 5.18957329214193 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.12821337870369 | bayes_pls_golite062009 |
| growth factor activity | 4.72461268561406 | bayes_pls_golite062009 |
| receptor binding | 4.33045214660893 | bayes_pls_golite062009 |
| protein binding | 3.02592228806142 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 2.88127286867262 | bayes_pls_golite062009 |
| heparin binding | 2.73820379449342 | bayes_pls_golite062009 |
| binding | 2.54996368217395 | bayes_pls_golite062009 |
| lipoprotein binding | 2.49586534030898 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 2.197145317433 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 2.04860930279383 | bayes_pls_golite062009 |
| lipoprotein receptor activity | 1.88531190199688 | bayes_pls_golite062009 |
| low-density lipoprotein binding | 1.76602889313095 | bayes_pls_golite062009 |
| molecular transducer activity | 1.66401431847753 | bayes_pls_golite062009 |
| signal transducer activity | 1.66401431847753 | bayes_pls_golite062009 |
| polysaccharide binding | 1.52943230565474 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 1.45792086043869 | bayes_pls_golite062009 |
| transporter activity | 1.44005597324471 | bayes_pls_golite062009 |
| pattern binding | 1.40261567769805 | bayes_pls_golite062009 |
| collagen binding | 1.3611207932336 | bayes_pls_golite062009 |
| transcription factor binding | 1.35328446721926 | bayes_pls_golite062009 |
| low-density lipoprotein receptor activity | 1.33530873314599 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.08803800589535 | bayes_pls_golite062009 |
| Wnt receptor activity | 0.91033392909889 | bayes_pls_golite062009 |
| transcription regulator activity | 0.724489340907325 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 0.6530199085873 | bayes_pls_golite062009 |
| apolipoprotein binding | 0.598690562495919 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.50737750327034 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.44857826904729 | bayes_pls_golite062009 |
| carbohydrate binding | 0.37481112933019 | bayes_pls_golite062009 |
| extracellular matrix binding | 0.3265100728106 | bayes_pls_golite062009 |
| glycoprotein binding | 0.128291636237359 | bayes_pls_golite062009 |
| protein transporter activity | 0.0566254663933097 | bayes_pls_golite062009 |
|
Region A: Residues: [419-664] |
1 11 21 31 41 51
| | | | | |
1 DSPDYTIFPL PLGKVKYAIA IDYDPVEEHI YWSDVETYTI KRAHADGTGV TDFVTSEVRH 60
61 PDGLALDWLA RNLYWTDTVT DRIEVCRLDG TARKVLIYEH LEEPRAIAVA PSLGWMFWSD 120
121 WNERKPKVER ASLDGSERVV LVSENLGWPN GIALDIEAKA IYWCDGKTDK IEVANMDGSG 180
181 RRVVISDNLK HLFGLSILDD YLYWTDWQRR SIDRAHKITG NNRIVVVDQY PDLMGLKVTR 240
241 LREVRG
|
| Detection Method: | |
| Confidence: | 75.0 |
| Match: | 1npeA |
| Description: | Crystal structure of Nidogen/Laminin Complex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| receptor activity | 5.18957329214193 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.12821337870369 | bayes_pls_golite062009 |
| molecular transducer activity | 4.28859337937742 | bayes_pls_golite062009 |
| signal transducer activity | 4.28859337937742 | bayes_pls_golite062009 |
| protein binding | 3.16714127217673 | bayes_pls_golite062009 |
| binding | 2.67985823019393 | bayes_pls_golite062009 |
| growth factor activity | 2.52088398765308 | bayes_pls_golite062009 |
| lipoprotein binding | 2.49586534030898 | bayes_pls_golite062009 |
| lipoprotein receptor activity | 1.88531190199688 | bayes_pls_golite062009 |
| low-density lipoprotein binding | 1.76602889313095 | bayes_pls_golite062009 |
| receptor binding | 1.72672102029619 | bayes_pls_golite062009 |
| transporter activity | 1.44005597324471 | bayes_pls_golite062009 |
| collagen binding | 1.3611207932336 | bayes_pls_golite062009 |
| low-density lipoprotein receptor activity | 1.33530873314599 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.08803800589535 | bayes_pls_golite062009 |
| Wnt receptor activity | 0.91033392909889 | bayes_pls_golite062009 |
| apolipoprotein binding | 0.598690562495919 | bayes_pls_golite062009 |
| extracellular matrix binding | 0.3265100728106 | bayes_pls_golite062009 |
| protein transporter activity | 0.0566254663933097 | bayes_pls_golite062009 |
|
Region A: Residues: [665-756] |
1 11 21 31 41 51
| | | | | |
1 QNACAVRNGG CSHLCLNRPR DYVCRCAIDY ELANDKRTCV VPAAFLLFSR QEHIGRISIE 60
61 YNEGNHNDER IPFKDVRDAH ALDVSVAERR IY
|
| Detection Method: | |
| Confidence: | 4.79 |
| Match: | 1n7dA |
| Description: | Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| growth factor activity | 4.33479937975628 | bayes_pls_golite062009 |
| receptor binding | 3.99541876330624 | bayes_pls_golite062009 |
| protein binding | 2.87649191391668 | bayes_pls_golite062009 |
| heparin binding | 2.45922265758085 | bayes_pls_golite062009 |
| binding | 2.4527651483634 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 2.28286857040435 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 1.79528213050973 | bayes_pls_golite062009 |
| molecular transducer activity | 1.66370136016696 | bayes_pls_golite062009 |
| signal transducer activity | 1.66370136016696 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.62745846687818 | bayes_pls_golite062009 |
| polysaccharide binding | 1.29534342979498 | bayes_pls_golite062009 |
| pattern binding | 1.18858604250595 | bayes_pls_golite062009 |
| transcription factor binding | 1.12709437655272 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 0.938743965687308 | bayes_pls_golite062009 |
| transcription regulator activity | 0.654704378168009 | bayes_pls_golite062009 |
| extracellular matrix structural constituent | 0.522998725269686 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.346221179082765 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.237963823897778 | bayes_pls_golite062009 |
| carbohydrate binding | 0.221914592276874 | bayes_pls_golite062009 |
| catalytic activity | 0.0197550253779933 | bayes_pls_golite062009 |
|
Region A: Residues: [757-1250] |
1 11 21 31 41 51
| | | | | |
1 WTDQKSKCIF RAFLNGSYVQ RIVDSGLIGP DGIAVDWLAN NIYWSDAEAR RIEVARLDGS 60
61 SRRVLLWKGV EEPRSLVLEP RRGYMYWTES PTDSIRRAAM DGSDLQTIVA GANHAAGLTF 120
121 DQETRRLYWA TQSRPAKIES ADWDGKKRQI LVGSDMDEPY AVSLYQDYVY WSDWNTGDIE 180
181 RVHKTTGQNR SLVHSGMTYI TSLLVFNDKR QTGVNPCKVN NGGCSHLCLA QPGRRGMTCA 240
241 CPTHYQLAKD GVSCIPPRNY IIFSQRNCFG RLLPNTTDCP NIPLPVSGKN IRAVDYDPIT 300
301 HHIYWIEGRS HSIKRSLANG TKVSLLANSG QPFDLAIDII GRLLFWTCSQ SNSINVTSFL 360
361 GESVGVIDTG DSEKPRNIAV HAMKRLLFWT DVGSHQAIIR ARVDGNERVE LAYKLEGVTA 420
421 LALDQQSDMI YYAHGKRIDA IDINGKNKKT LVSMHISQVI NIAALGGFVY WLDDKTGVER 480
481 ITVNGERRSA ELQR
|
| Detection Method: | |
| Confidence: | 3.93 |
| Match: | 2z2nA |
| Description: | No description for 2z2nA was found. |
|
Region A: Residues: [1251-1290] |
1 11 21 31 41 51
| | | | | |
1 LPQITDIRAV WTPDPKVLRN HTCMHSRTKC SHICIASGEG
|
| Detection Method: | |
| Confidence: | 5.0 |
| Match: | 2dtgE |
| Description: | No description for 2dtgE was found. |
|
Region A: Residues: [1291-1678] |
1 11 21 31 41 51
| | | | | |
1 IARTRDVCSC PKHLMLLEDK ENCGAFPACG PDHFTCAAPV SGISDVNKDC IPASWRCDGQ 60
61 KDCPDKSDEV GCPTCRADQF SCQSGECIDK SLVCDGTTNC ANGHDEADCC KRPGEFQCPI 120
121 NKLCISAALL CDGWENCADG ADESSDICLQ RRMAPATDKR AFMILIGATM ITIFSIVYLL 180
181 QFCRTRIGKS RTEPKDDQAT DPLSPSTLSK SQRVSKIASV ADAVRMSTLN SRNSMNSYDR 240
241 NHITGASSST TNGSSMVAYP INPPPSPATR SRRPYRHYKI INQPPPPTPC STDICDESDS 300
301 NYTSKSNSNN SNGGATKHSS SSAAACLQYG YDSEPYPPPP TPRSHYHSDV RIVPESSCPP 360
361 SPSSRSSTYF SPLPPPPSPV QSPSRGFT
|
| Detection Method: | |
| Confidence: | 5.522879 |
| Match: | 1yo8A |
| Description: | Strucuture of the C-terminal domain of human thrombospondin-2 |
Matching Structure (courtesy of the PDB): |
|
