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View Structure Prediction Details

Protein: CSN7-PA
Organism: Drosophila melanogaster
Length: 278 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CSN7-PA.

Description E-value Query
Range
Subject
Range
gi|50752333 - gi|50752333|ref|XP_422740.1| PREDICTED: similar to Cops7b protein [Gallus gallus]
265.0 [0..6] [270..244]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQDMLLGNE EPSKSKETFL EKFCVLAKSS TGAALLDVIR QALEAPNVFV FGELLAEPSV  60
   61 LQLKDGPDSK HFETLNLFAY GTYKEYRAQP EKFIELTPAM Q

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [102-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKLQHLTIVS LAIKAKSIPY ALLLSELEID NVRHLEDIII EAIYADIIHG KLFQNTRILE  60
   61 VDYAQGRDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.09178084244715 bayes_pls_golite062009
DNA binding 4.69269372393889 bayes_pls_golite062009
nucleic acid binding 4.59221092058767 bayes_pls_golite062009
binding 4.100002699956 bayes_pls_golite062009
transcription factor activity 4.01234546864709 bayes_pls_golite062009
sequence-specific DNA binding 2.23304004014963 bayes_pls_golite062009
transcription activator activity 2.21230033124772 bayes_pls_golite062009
transcription repressor activity 2.09951094757211 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.40206639526766 bayes_pls_golite062009
transcription factor binding 0.78051974537344 bayes_pls_golite062009
protein binding 0.653872239015235 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [171-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPGYTGQIVE TLQAWVNSCD SVSNCIEMQI KYANAEKSKR LINKERVEQD LINLKKVLKS  60
   61 QTSDSDESMQ IDTHGPGTSG GLGQSELRKK PSKLRNPRSA AVGLKFSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle